Luo BH - Search Results

1

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand.

Luo BH, Springer TA, Takagi J. Luo BH, et al. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2403-8. doi: 10.1073/pnas.0438060100. Epub 2003 Feb 25. Proc Natl Acad Sci U S A. 2003. PMID: 12604783 Free PMC article.

2

High affinity ligand binding by integrins does not involve head separation.

Luo BH, Springer TA, Takagi J. Luo BH, et al. J Biol Chem. 2003 May 9;278(19):17185-9. doi: 10.1074/jbc.M301516200. Epub 2003 Feb 24. J Biol Chem. 2003. PMID: 12600996 Free article.

3

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides.

Luo BH, Takagi J, Springer TA. Luo BH, et al. J Biol Chem. 2004 Mar 12;279(11):10215-21. doi: 10.1074/jbc.M312732200. Epub 2003 Dec 16. J Biol Chem. 2004. PMID: 14681220 Free article.

4

Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain.

Luo BH, Strokovich K, Walz T, Springer TA, Takagi J. Luo BH, et al. J Biol Chem. 2004 Jun 25;279(26):27466-71. doi: 10.1074/jbc.M404354200. Epub 2004 Apr 27. J Biol Chem. 2004. PMID: 15123676 Free article.

5

A specific interface between integrin transmembrane helices and affinity for ligand.

Luo BH, Springer TA, Takagi J. Luo BH, et al. PLoS Biol. 2004 Jun;2(6):e153. doi: 10.1371/journal.pbio.0020153. Epub 2004 Jun 15. PLoS Biol. 2004. PMID: 15208712 Free PMC article.

6

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

Chen J, Takagi J, Xie C, Xiao T, Luo BH, Springer TA. Chen J, et al. Among authors: luo bh. J Biol Chem. 2004 Dec 31;279(53):55556-61. doi: 10.1074/jbc.M407773200. Epub 2004 Sep 24. J Biol Chem. 2004. PMID: 15448154 Free PMC article.

7

Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.

Luo BH, Carman CV, Takagi J, Springer TA. Luo BH, et al. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3679-84. doi: 10.1073/pnas.0409440102. Epub 2005 Feb 28. Proc Natl Acad Sci U S A. 2005. PMID: 15738420 Free PMC article.

8

Integrin structures and conformational signaling.

Luo BH, Springer TA. Luo BH, et al. Curr Opin Cell Biol. 2006 Oct;18(5):579-86. doi: 10.1016/j.ceb.2006.08.005. Epub 2006 Aug 14. Curr Opin Cell Biol. 2006. PMID: 16904883 Free PMC article. Review.

9

Structural basis of integrin regulation and signaling.

Luo BH, Carman CV, Springer TA. Luo BH, et al. Annu Rev Immunol. 2007;25:619-47. doi: 10.1146/annurev.immunol.25.022106.141618. Annu Rev Immunol. 2007. PMID: 17201681 Free PMC article. Review.

10

Tests of the extension and deadbolt models of integrin activation.

Zhu J, Boylan B, Luo BH, Newman PJ, Springer TA. Zhu J, et al. Among authors: luo bh. J Biol Chem. 2007 Apr 20;282(16):11914-20. doi: 10.1074/jbc.M700249200. Epub 2007 Feb 13. J Biol Chem. 2007. PMID: 17301049 Free PMC article.

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