Owen KR - Search Results

1

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.

Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM. Gloyn AL, et al. Among authors: owen kr. Diabetes. 2003 Feb;52(2):568-72. doi: 10.2337/diabetes.52.2.568. Diabetes. 2003. PMID: 12540637

2

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.

Frayling TM, Evans JC, Bulman MP, Pearson E, Allen L, Owen K, Bingham C, Hannemann M, Shepherd M, Ellard S, Hattersley AT. Frayling TM, et al. Diabetes. 2001 Feb;50 Suppl 1:S94-100. doi: 10.2337/diabetes.50.2007.s94. Diabetes. 2001. PMID: 11272211

3

Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization.

Owen K, Hattersley AT. Owen K, et al. Best Pract Res Clin Endocrinol Metab. 2001 Sep;15(3):309-23. doi: 10.1053/beem.2001.0148. Best Pract Res Clin Endocrinol Metab. 2001. PMID: 11554773 Review.

4

Increased risk of diabetes in first-degree relatives of young-onset type 2 diabetic patients compared with relatives of those diagnosed later.

Owen K, Ayres S, Corbett S, Hattersley A. Owen K, et al. Diabetes Care. 2002 Mar;25(3):636-7. doi: 10.2337/diacare.25.3.636. Diabetes Care. 2002. PMID: 11874970 No abstract available.

5

Association studies of genetic variation in the WFS1 gene and type 2 diabetes in U.K. populations.

Minton JA, Hattersley AT, Owen K, McCarthy MI, Walker M, Latif F, Barrett T, Frayling TM. Minton JA, et al. Diabetes. 2002 Apr;51(4):1287-90. doi: 10.2337/diabetes.51.4.1287. Diabetes. 2002. PMID: 11916957

6

The role of the HNF4alpha enhancer in type 2 diabetes.

Mitchell SM, Gloyn AL, Owen KR, Hattersley AT, Frayling TM. Mitchell SM, et al. Among authors: owen kr. Mol Genet Metab. 2002 Jun;76(2):148-51. doi: 10.1016/S1096-7192(02)00027-6. Mol Genet Metab. 2002. PMID: 12083813

7

A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations.

Frayling TM, Hattersley AT, McCarthy A, Holly J, Mitchell SM, Gloyn AL, Owen K, Davies D, Smith GD, Ben-Shlomo Y. Frayling TM, et al. Diabetes. 2002 Jul;51(7):2313-6. doi: 10.2337/diabetes.51.7.2313. Diabetes. 2002. PMID: 12086966

8

Heterogeneity in young adult onset diabetes: aetiology alters clinical characteristics.

Owen KR, Shepherd M, Stride A, Ellard S, Hattersley AT. Owen KR, et al. Diabet Med. 2002 Sep;19(9):758-61. doi: 10.1046/j.1464-5491.2002.00766.x. Diabet Med. 2002. PMID: 12207813

9

Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes.

Mitchell SM, Vaxillaire M, Thomas H, Parrizas M, Benmezroua Y, Costa A, Hansen T, Owen KR, Tuomi T, Pirie F, Ryffel GU, Ferrer J, Froguel P, Hattersley AT, Frayling TM. Mitchell SM, et al. Among authors: owen kr. Diabetologia. 2002 Sep;45(9):1344-8. doi: 10.1007/s00125-002-0913-7. Epub 2002 Jul 19. Diabetologia. 2002. PMID: 12242469

10

Atypical familial juvenile hyperuricemic nephropathy associated with a hepatocyte nuclear factor-1beta gene mutation.

Bingham C, Ellard S, van't Hoff WG, Simmonds HA, Marinaki AM, Badman MK, Winocour PH, Stride A, Lockwood CR, Nicholls AJ, Owen KR, Spyer G, Pearson ER, Hattersley AT. Bingham C, et al. Among authors: owen kr. Kidney Int. 2003 May;63(5):1645-51. doi: 10.1046/j.1523-1755.2003.00903.x. Kidney Int. 2003. PMID: 12675839 Free article.

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