Beeton C - Search Results

1

A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes.

Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. Beeton C, et al. J Biol Chem. 2003 Mar 14;278(11):9928-37. doi: 10.1074/jbc.M212868200. Epub 2003 Jan 2. J Biol Chem. 2003. PMID: 12511563 Free article.

2

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis.

Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Béraud E. Beeton C, et al. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13942-7. doi: 10.1073/pnas.241497298. Proc Natl Acad Sci U S A. 2001. PMID: 11717451 Free PMC article.

3

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.

Wulff H, Calabresi PA, Allie R, Yun S, Pennington M, Beeton C, Chandy KG. Wulff H, et al. Among authors: beeton c. J Clin Invest. 2003 Jun;111(11):1703-13. doi: 10.1172/JCI16921. J Clin Invest. 2003. PMID: 12782673 Free PMC article.

4

Potassium channels as therapeutic targets for autoimmune disorders.

Wulff H, Beeton C, Chandy KG. Wulff H, et al. Among authors: beeton c. Curr Opin Drug Discov Devel. 2003 Sep;6(5):640-7. Curr Opin Drug Discov Devel. 2003. PMID: 14579513 Review.

5

K+ channels as targets for specific immunomodulation.

Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. Chandy KG, et al. Among authors: beeton c. Trends Pharmacol Sci. 2004 May;25(5):280-9. doi: 10.1016/j.tips.2004.03.010. Trends Pharmacol Sci. 2004. PMID: 15120495 Free PMC article. Review.

6

Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Vennekamp J, Wulff H, Beeton C, Calabresi PA, Grissmer S, Hänsel W, Chandy KG. Vennekamp J, et al. Among authors: beeton c. Mol Pharmacol. 2004 Jun;65(6):1364-74. doi: 10.1124/mol.65.6.1364. Mol Pharmacol. 2004. PMID: 15155830

7

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases.

Beeton C, Pennington MW, Wulff H, Singh S, Nugent D, Crossley G, Khaytin I, Calabresi PA, Chen CY, Gutman GA, Chandy KG. Beeton C, et al. Mol Pharmacol. 2005 Apr;67(4):1369-81. doi: 10.1124/mol.104.008193. Epub 2005 Jan 21. Mol Pharmacol. 2005. PMID: 15665253 Free PMC article.

8

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

Rus H, Pardo CA, Hu L, Darrah E, Cudrici C, Niculescu T, Niculescu F, Mullen KM, Allie R, Guo L, Wulff H, Beeton C, Judge SI, Kerr DA, Knaus HG, Chandy KG, Calabresi PA. Rus H, et al. Among authors: beeton c. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11094-9. doi: 10.1073/pnas.0501770102. Epub 2005 Jul 25. Proc Natl Acad Sci U S A. 2005. PMID: 16043714 Free PMC article.

9

Potassium channels, memory T cells, and multiple sclerosis.

Beeton C, Chandy KG. Beeton C, et al. Neuroscientist. 2005 Dec;11(6):550-62. doi: 10.1177/1073858405278016. Neuroscientist. 2005. PMID: 16282596 Review.

10

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, LeeHealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, Knaus HG, Nepom GT, Gutman GA, Calabresi PA, Chandy KG. Beeton C, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17414-9. doi: 10.1073/pnas.0605136103. Epub 2006 Nov 6. Proc Natl Acad Sci U S A. 2006. PMID: 17088564 Free PMC article.

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