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Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.
Rescourio G, Gonzalez AZ, Jabri S, Belmontes B, Moody G, Whittington D, Huang X, Caenepeel S, Cardozo M, Cheng AC, Chow D, Dou H, Jones A, Kelly RC, Li Y, Lizarzaburu M, Lo MC, Mallari R, Meleza C, Rew Y, Simonovich S, Sun D, Turcotte S, Yan X, Wong SG, Yanez E, Zancanella M, Houze J, Medina JC, Hughes PE, Brown SP. Rescourio G, et al. J Med Chem. 2019 Nov 27;62(22):10258-10271. doi: 10.1021/acs.jmedchem.9b01310. Epub 2019 Nov 18. J Med Chem. 2019. PMID: 31736296
Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility.
Rzasa RM, Frohn MJ, Andrews KL, Chmait S, Chen N, Clarine JG, Davis C, Eastwood HA, Horne DB, Hu E, Jones AD, Kaller MR, Kunz RK, Miller S, Monenschein H, Nguyen T, Pickrell AJ, Porter A, Reichelt A, Zhao X, Treanor JJS, Allen JR. Rzasa RM, et al. Among authors: jones ad. Bioorg Med Chem. 2014 Dec 1;22(23):6570-6585. doi: 10.1016/j.bmc.2014.10.013. Bioorg Med Chem. 2014. PMID: 25456383
Using Novel Multimethod Evaluation Approaches to Understand Complex Food System Interventions: Insights from a Supply Chain Intervention Intended to Improve Nutrition.
Maredia MK, Nakasone E, Porter M, Nordhagen S, Caputo V, Djimeu EW, Jones AD, Mbuya MN, Ortega DL, Toure D, Tschirley D. Maredia MK, et al. Among authors: jones ad. Curr Dev Nutr. 2024 May 25;8(6):103776. doi: 10.1016/j.cdnut.2024.103776. eCollection 2024 Jun. Curr Dev Nutr. 2024. PMID: 38979104 Free PMC article.
The Climate Change Burden on Immune Health: Are Persons Living with HIV More at Risk?
Woolley G, Kroll K, Hoffman K, Ward A, Corneli A, Mudrak SV, Qureshi MU, Okeke NL, Chan C, Jones AD, Tomaras GD, Reeves RK. Woolley G, et al. Among authors: jones ad. AIDS Res Hum Retroviruses. 2024 Oct;40(10):549-554. doi: 10.1089/AID.2024.0050. Epub 2024 May 27. AIDS Res Hum Retroviruses. 2024. PMID: 38753709
514 results