Antoine MH - Search Results

1

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ. Cosgrove KE, et al. Among authors: antoine mh. J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8. doi: 10.1210/jc.2002-020439. J Clin Endocrinol Metab. 2002. PMID: 12414839

2

In vitro and in vivo effects of new insulin releasing agents.

Nguyen QA, Antoine MH, Ouedraogo R, Hermann M, Sergooris J, Pirotte B, Masereel B, Lebrun P. Nguyen QA, et al. Among authors: antoine mh. Biochem Pharmacol. 2002 Feb 1;63(3):515-21. doi: 10.1016/s0006-2952(01)00880-2. Biochem Pharmacol. 2002. PMID: 11853702

3

4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone.

Sebille S, de Tullio P, Becker B, Antoine MH, Boverie S, Pirotte B, Lebrun P. Sebille S, et al. Among authors: antoine mh. J Med Chem. 2005 Jan 27;48(2):614-21. doi: 10.1021/jm040789e. J Med Chem. 2005. PMID: 15658874

4

Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.

Boverie S, Antoine MH, Somers F, Becker B, Sebille S, Ouedraogo R, Counerotte S, Pirotte B, Lebrun P, de Tullio P. Boverie S, et al. Among authors: antoine mh. J Med Chem. 2005 May 19;48(10):3492-503. doi: 10.1021/jm0311339. J Med Chem. 2005. PMID: 15887958

5

3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: effect of 6,7-disubstitution on potency and tissue selectivity.

de Tullio P, Boverie S, Becker B, Antoine MH, Nguyen QA, Francotte P, Counerotte S, Sebille S, Pirotte B, Lebrun P. de Tullio P, et al. Among authors: antoine mh. J Med Chem. 2005 Jul 28;48(15):4990-5000. doi: 10.1021/jm0580050. J Med Chem. 2005. PMID: 16033278

6

Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides.

de Tullio P, Becker B, Boverie S, Dabrowski M, Wahl P, Antoine MH, Somers F, Sebille S, Ouedraogo R, Hansen JB, Lebrun P, Pirotte B. de Tullio P, et al. Among authors: antoine mh. J Med Chem. 2003 Jul 17;46(15):3342-53. doi: 10.1021/jm021117w. J Med Chem. 2003. PMID: 12852765

7

2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?

Ouedraogo R, Becker B, Boverie S, Somers F, Antoine MH, Pirotte B, Lebrun P, de Tullio P. Ouedraogo R, et al. Among authors: antoine mh. Biol Chem. 2002 Nov;383(11):1759-68. doi: 10.1515/BC.2002.197. Biol Chem. 2002. PMID: 12530541

8

KATP channel openers: tissue selectivity of original 3-alkylaminopyrido- and 3-alkylaminobenzothiadiazine 1,1-dioxides.

Lebrun P, Becker B, Morel N, Ghisdal P, Antoine MH, de Tullio P, Pirotte B. Lebrun P, et al. Among authors: antoine mh. Biochem Pharmacol. 2008 Jan 15;75(2):468-75. doi: 10.1016/j.bcp.2007.08.032. Epub 2007 Sep 1. Biochem Pharmacol. 2008. PMID: 17920043

9

New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers.

Sebille S, de Tullio P, Florence X, Becker B, Antoine MH, Michaux C, Wouters J, Pirotte B, Lebrun P. Sebille S, et al. Among authors: antoine mh. Bioorg Med Chem. 2008 May 15;16(10):5704-19. doi: 10.1016/j.bmc.2008.03.065. Epub 2008 Mar 30. Bioorg Med Chem. 2008. PMID: 18406154

10

Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.

Tagmose TM, Schou SC, Mogensen JP, Nielsen FE, Arkhammar PO, Wahl P, Hansen BS, Worsaae A, Boonen HC, Antoine MH, Lebrun P, Hansen JB. Tagmose TM, et al. Among authors: antoine mh. J Med Chem. 2004 Jun 3;47(12):3202-11. doi: 10.1021/jm031018y. J Med Chem. 2004. PMID: 15163199

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