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Page 1
Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK.
Cuadrado A, Garcia-Fernandez LF, Gonzalez L, Suarez Y, Losada A, Alcaide V, Martinez T, Fernandez-Sousa JM, Sanchez-Puelles JM, Munoz A. Cuadrado A, et al. Among authors: martinez t. J Biol Chem. 2003 Jan 3;278(1):241-50. doi: 10.1074/jbc.M201010200. Epub 2002 Oct 31. J Biol Chem. 2003. PMID: 12414812 Free article.
JNK activation is critical for Aplidin-induced apoptosis.
Cuadrado A, González L, Suárez Y, Martínez T, Muñoz A. Cuadrado A, et al. Among authors: martinez t. Oncogene. 2004 Jun 10;23(27):4673-80. doi: 10.1038/sj.onc.1207636. Oncogene. 2004. PMID: 15122339
Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation.
González-Santiago L, Suárez Y, Zarich N, Muñoz-Alonso MJ, Cuadrado A, Martínez T, Goya L, Iradi A, Sáez-Tormo G, Maier JV, Moorthy A, Cato AC, Rojas JM, Muñoz A. González-Santiago L, et al. Among authors: martinez t. Cell Death Differ. 2006 Nov;13(11):1968-81. doi: 10.1038/sj.cdd.4401898. Epub 2006 Mar 17. Cell Death Differ. 2006. PMID: 16543941
The mechanism of action of plitidepsin.
Muñoz-Alonso MJ, González-Santiago L, Martínez T, Losada A, Galmarini CM, Muñoz A. Muñoz-Alonso MJ, et al. Among authors: martinez t. Curr Opin Investig Drugs. 2009 Jun;10(6):536-42. Curr Opin Investig Drugs. 2009. PMID: 19513942 Review.
Targeting body composition in an older population: do changes in movement behaviours matter? Longitudinal analyses in the PREDIMED-Plus trial.
Galmes-Panades AM, Konieczna J, Varela-Mato V, Abete I, Babio N, Fiol M, Antonio de Paz J, Casas R, Olbeyra R, Ruiz-Canela M, Palau-Galindo A, Castañer O, Martín-García A, Estruch R, Vidal J, Buil-Cosiales P, Wärnberg J, Salas-Salvadó J, Martínez JA, Romaguera D; PREDIMED-Plus investigators. Galmes-Panades AM, et al. BMC Med. 2021 Jan 6;19(1):3. doi: 10.1186/s12916-020-01847-9. BMC Med. 2021. PMID: 33402165 Free PMC article. Clinical Trial.
Cross-sectional association between non-soy legume consumption, serum uric acid and hyperuricemia: the PREDIMED-Plus study.
Becerra-Tomás N, Mena-Sánchez G, Díaz-López A, Martínez-González MÁ, Babio N, Corella D, Freixer G, Romaguera D, Vioque J, Alonso-Gómez ÁM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Fernández-García JC, Lapetra J, Pintó X, Tur JA, López-Miranda J, Bueno-Cavanillas A, Gaforio JJ, Matía-Martín P, Daimiel L, Martín-Sánchez V, Vidal J, Vázquez C, Ros E, Razquin C, Abellán Cano I, Sorli JV, Torres L, Morey M, Navarrete-Muñoz EM, Tojal Sierra L, Crespo-Oliva E, Zulet MÁ, Sanchez-Villegas A, Casas R, Bernal-Lopez MR, Santos-Lozano JM, Corbella E, Del Mar Bibiloni M, Ruiz-Canela M, Fernández-Carrión R, Quifer M, Prieto RM, Fernandez-Brufal N, Salaverria Lete I, Cenoz JC, Llimona R, Salas-Salvadó J; PREDIMED-Plus Investigators. Becerra-Tomás N, et al. Eur J Nutr. 2020 Aug;59(5):2195-2206. doi: 10.1007/s00394-019-02070-w. Epub 2019 Aug 5. Eur J Nutr. 2020. PMID: 31385063
Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population.
Paz-Graniel I, Babio N, Becerra-Tomás N, Toledo E, Camacho-Barcia L, Corella D, Castañer-Niño O, Romaguera D, Vioque J, Alonso-Gómez ÁM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Tinahones FJ, Fernandez-Aranda F, Lapetra J, Pintó X, Tur JA, García-Rios A, Bueno-Cavanillas A, Gaforio JJ, Matía-Martín P, Daimiel L, Sánchez VM, Vidal J, Prieto-Sanchez L, Ros E, Razquin C, Mestres C, Sorli JV, Cuenca-Royo AM, Rios A, Torres-Collado L, Vaquero-Luna J, Pérez-Farinós N, Zulet MA, Sanchez-Villegas A, Casas R, Bernal-Lopez MR, Santos-Lozano JM, Corbella X, Mateos D, Buil-Cosiales P, Jiménez-Murcia S, Fernandez-Carrion R, Forcano-Gamazo L, López M, Sempere-Pascual MÁ, Moreno-Rodriguez A, Gea A, de la Torre-Fornell R, Salas-Salvadó J; PREDIMED-Plus Investigators. Paz-Graniel I, et al. Eur J Nutr. 2021 Aug;60(5):2381-2396. doi: 10.1007/s00394-020-02415-w. Epub 2020 Oct 30. Eur J Nutr. 2021. PMID: 33125576
839 results