Marhefka CA - Search Results

1

Structure and dynamics of thioguanine-modified duplex DNA.

Somerville L, Krynetski EY, Krynetskaia NF, Beger RD, Zhang W, Marhefka CA, Evans WE, Kriwacki RW. Somerville L, et al. Among authors: marhefka ca. J Biol Chem. 2003 Jan 10;278(2):1005-11. doi: 10.1074/jbc.M204243200. Epub 2002 Oct 24. J Biol Chem. 2003. PMID: 12401802 Free article.

2

Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.

Marhefka CA, Moore BM 2nd, Bishop TC, Kirkovsky L, Mukherjee A, Dalton JT, Miller DD. Marhefka CA, et al. J Med Chem. 2001 May 24;44(11):1729-40. doi: 10.1021/jm0005353. J Med Chem. 2001. PMID: 11356108

3

Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators.

Marhefka CA, Gao W, Chung K, Kim J, He Y, Yin D, Bohl C, Dalton JT, Miller DD. Marhefka CA, et al. J Med Chem. 2004 Feb 12;47(4):993-8. doi: 10.1021/jm030336u. J Med Chem. 2004. PMID: 14761201 Free PMC article.

4

Pharmacodynamics of selective androgen receptor modulators.

Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT. Yin D, et al. Among authors: marhefka ca. J Pharmacol Exp Ther. 2003 Mar;304(3):1334-40. doi: 10.1124/jpet.102.040840. J Pharmacol Exp Ther. 2003. PMID: 12604714

5

Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

Yin D, He Y, Perera MA, Hong SS, Marhefka C, Stourman N, Kirkovsky L, Miller DD, Dalton JT. Yin D, et al. Mol Pharmacol. 2003 Jan;63(1):211-23. doi: 10.1124/mol.63.1.211. Mol Pharmacol. 2003. PMID: 12488554

6

Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors.

Green J, Cao J, Bandarage UK, Gao H, Court J, Marhefka C, Jacobs M, Taslimi P, Newsome D, Nakayama T, Shah S, Rodems S. Green J, et al. J Med Chem. 2015 Jun 25;58(12):5028-37. doi: 10.1021/acs.jmedchem.5b00424. Epub 2015 Jun 12. J Med Chem. 2015. PMID: 26039570

7

ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.

Bandarage UK, Cao J, Come JH, Court JJ, Gao H, Jacobs MD, Marhefka C, Nanthakumar S, Green J. Bandarage UK, et al. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2622-2626. doi: 10.1016/j.bmcl.2018.06.040. Epub 2018 Jun 19. Bioorg Med Chem Lett. 2018. PMID: 30082069

8

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.

Bandarage U, Hare B, Parsons J, Pham L, Marhefka C, Bemis G, Tang Q, Moody CS, Rodems S, Shah S, Adams C, Bravo J, Charonnet E, Savic V, Come JH, Green J. Bandarage U, et al. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5191-4. doi: 10.1016/j.bmcl.2009.07.022. Epub 2009 Jul 9. Bioorg Med Chem Lett. 2009. PMID: 19632115

9

ROCK inhibitors 2. Improving potency, selectivity and solubility through the application of rationally designed solubilizing groups.

Gao H, Marhefka C, Jacobs MD, Cao J, Bandarage UK, Green J. Gao H, et al. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2616-2621. doi: 10.1016/j.bmcl.2018.06.043. Epub 2018 Jun 21. Bioorg Med Chem Lett. 2018. PMID: 29945794

10

Trace detection of meglumine and diatrizoate from Bacillus spore samples using liquid chromatography/mass spectrometry.

Swider C, Maguire K, Rickenbach M, Montgomery M, Ducote MJ, Marhefka CA. Swider C, et al. Among authors: marhefka ca. J Forensic Sci. 2012 Jul;57(4):923-31. doi: 10.1111/j.1556-4029.2012.02128.x. Epub 2012 Apr 26. J Forensic Sci. 2012. PMID: 22537353

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