Umans L - Search Results

1

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.

Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, Annaert W, Umans L, Lübke T, Lena Illert A, von Figura K, Saftig P. Hartmann D, et al. Among authors: umans l. Hum Mol Genet. 2002 Oct 1;11(21):2615-24. doi: 10.1093/hmg/11.21.2615. Hum Mol Genet. 2002. PMID: 12354787

2

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency.

Herreman A, Hartmann D, Annaert W, Saftig P, Craessaerts K, Serneels L, Umans L, Schrijvers V, Checler F, Vanderstichele H, Baekelandt V, Dressel R, Cupers P, Huylebroeck D, Zwijsen A, Van Leuven F, De Strooper B. Herreman A, et al. Among authors: umans l. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11872-7. doi: 10.1073/pnas.96.21.11872. Proc Natl Acad Sci U S A. 1999. PMID: 10518543 Free PMC article.

3

Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.

De Strooper B, Umans L, Van Leuven F, Van Den Berghe H. De Strooper B, et al. Among authors: umans l. J Cell Biol. 1993 Apr;121(2):295-304. doi: 10.1083/jcb.121.2.295. J Cell Biol. 1993. PMID: 8468348 Free PMC article.

4

Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.

Umans L, Serneels L, Hilliker C, Stas L, Overbergh L, De Strooper B, Van Leuven F, Van den Berghe H. Umans L, et al. Genomics. 1994 Aug;22(3):519-29. doi: 10.1006/geno.1994.1425. Genomics. 1994. PMID: 7528166

5

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

Umans L, Serneels L, Overbergh L, Lorent K, Van Leuven F, Van den Berghe H. Umans L, et al. J Biol Chem. 1995 Aug 25;270(34):19778-85. doi: 10.1074/jbc.270.34.19778. J Biol Chem. 1995. PMID: 7544347 Free article.

6

Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.

Van Leuven F, Hilliker C, Serneels L, Umans L, Overbergh L, De Strooper B, Fryns JP, Van den Berghe H. Van Leuven F, et al. Among authors: umans l. Genomics. 1995 Jan 20;25(2):492-500. doi: 10.1016/0888-7543(95)80050-v. Genomics. 1995. PMID: 7789983

7

alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.

Umans L, Serneels L, Overbergh L, Stas L, Van Leuven F. Umans L, et al. Am J Pathol. 1999 Sep;155(3):983-93. doi: 10.1016/s0002-9440(10)65198-x. Am J Pathol. 1999. PMID: 10487856 Free PMC article.

8

Analysis of expression of genes involved in apolipoprotein E-based lipoprotein metabolism in pregnant mice deficient in the receptor-associated protein, the low density lipoprotein receptor, or apolipoprotein E.

Umans L, Overbergh L, Serneels L, Tesseur I, Van Leuven F. Umans L, et al. Biol Reprod. 1999 Nov;61(5):1216-25. doi: 10.1095/biolreprod61.5.1216. Biol Reprod. 1999. PMID: 10529267

9

Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein.

Umans L, Serneels L, Lorent K, Dewachter I, Tesseur I, Moechars D, Van Leuven F. Umans L, et al. Neuroscience. 1999;94(1):315-21. doi: 10.1016/s0306-4522(99)00242-0. Neuroscience. 1999. PMID: 10613521

10

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

Dewachter I, Reversé D, Caluwaerts N, Ris L, Kuipéri C, Van den Haute C, Spittaels K, Umans L, Serneels L, Thiry E, Moechars D, Mercken M, Godaux E, Van Leuven F. Dewachter I, et al. Among authors: umans l. J Neurosci. 2002 May 1;22(9):3445-53. doi: 10.1523/JNEUROSCI.22-09-03445.2002. J Neurosci. 2002. PMID: 11978821 Free PMC article.

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