Prashad M - Search Results

1

An efficient and large-scale enantioselective synthesis of PNP405: a purine nucleoside phosphorylase inhibitor.

Prashad M, Har D, Chen L, Kim HY, Repic O, Blacklock TJ. Prashad M, et al. J Org Chem. 2002 Sep 20;67(19):6612-7. doi: 10.1021/jo020256i. J Org Chem. 2002. PMID: 12227788

2

The First Enantioselective Synthesis of (2R,2'R)-threo-(+)-Methylphenidate Hydrochloride.

Prashad M, Kim HY, Lu Y, Liu Y, Har D, Repic O, Blacklock TJ, Giannousis P. Prashad M, et al. J Org Chem. 1999 Mar 5;64(5):1750-1753. doi: 10.1021/jo9821473. J Org Chem. 1999. PMID: 11674251 No abstract available.

3

An efficient and practical N-methylation of amino acid derivatives.

Prashad M, Har D, Hu B, Kim HY, Repic O, Blacklock TJ. Prashad M, et al. Org Lett. 2003 Jan 23;5(2):125-8. doi: 10.1021/ol0268440. Org Lett. 2003. PMID: 12529121

4

A novel two-carbon homologation with N-vinylacetamides and ethyl vinyl ether as acetaldehyde anion equivalents in the synthesis of 9H-xanthene, 9H-thioxanthene, and 9,10-dihydro-9-acridine carboxaldehydes.

Prashad M, Lu Y, Repic O. Prashad M, et al. J Org Chem. 2004 Jan 23;69(2):584-6. doi: 10.1021/jo0303057. J Org Chem. 2004. PMID: 14725481

5

Enantioselective hydrogenation of alpha-aminomethylacrylates containing a free NH group for the synthesis of beta-amino acid derivatives.

Qiu L, Prashad M, Hu B, Prasad K, Repic O, Blacklock TJ, Kwong FY, Kok SH, Lee HW, Chan AS. Qiu L, et al. Among authors: prashad m. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16787-92. doi: 10.1073/pnas.0704461104. Epub 2007 Oct 17. Proc Natl Acad Sci U S A. 2007. PMID: 17942689 Free PMC article.

6

Palladium-catalyzed amination of aryl bromides with hindered N-alkyl-substituted anilines using a palladium(I) tri-tert-butylphosphine bromide dimer.

Prashad M, Mak XY, Liu Y, Repic O. Prashad M, et al. J Org Chem. 2003 Feb 7;68(3):1163-4. doi: 10.1021/jo020609d. J Org Chem. 2003. PMID: 12558453

7

beta-hydrogen-containing sodium alkoxides as suitable bases in palladium-catalyzed aminations of aryl halides.

Prashad M, Hu B, Lu Y, Draper R, Har D, Repic O, Blacklock TJ. Prashad M, et al. J Org Chem. 2000 Apr 21;65(8):2612-4. doi: 10.1021/jo991949a. J Org Chem. 2000. PMID: 10789487 No abstract available.

8

A scalable synthesis of an azabicyclooctanyl derivative, a novel DPP-4 inhibitor.

Fei Z, Wu Q, Zhang F, Cao Y, Liu C, Shieh WC, Xue S, McKenna J, Prasad K, Prashad M, Baeschlin D, Namoto K. Fei Z, et al. Among authors: prashad m. J Org Chem. 2008 Nov 21;73(22):9016-21. doi: 10.1021/jo801830x. Epub 2008 Oct 14. J Org Chem. 2008. PMID: 18850743

9

A facile asymmetric synthesis of either enantiomer of 2-substituted pyrrolidines.

Rajender Reddy L, Das SG, Liu Y, Prashad M. Rajender Reddy L, et al. Among authors: prashad m. J Org Chem. 2010 Apr 2;75(7):2236-46. doi: 10.1021/jo902710s. J Org Chem. 2010. PMID: 20201593

10

A protocol for an asymmetric synthesis of γ-amino acids.

Reddy LR, Prasad K, Prashad M. Reddy LR, et al. Among authors: prashad m. J Org Chem. 2012 Jul 20;77(14):6296-301. doi: 10.1021/jo301177f. Epub 2012 Jul 6. J Org Chem. 2012. PMID: 22747507

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