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Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics.
Dragovich PS, Prins TJ, Zhou R, Brown EL, Maldonado FC, Fuhrman SA, Zalman LS, Tuntland T, Lee CA, Patick AK, Matthews DA, Hendrickson TF, Kosa MB, Liu B, Batugo MR, Gleeson JP, Sakata SK, Chen L, Guzman MC, Meador JW 3rd, Ferre RA, Worland ST. Dragovich PS, et al. Among authors: chen l. J Med Chem. 2002 Apr 11;45(8):1607-23. doi: 10.1021/jm010469k. J Med Chem. 2002. PMID: 11931615
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics.
Dragovich PS, Prins TJ, Zhou R, Johnson TO, Hua Y, Luu HT, Sakata SK, Brown EL, Maldonado FC, Tuntland T, Lee CA, Fuhrman SA, Zalman LS, Patick AK, Matthews DA, Wu EY, Guo M, Borer BC, Nayyar NK, Moran T, Chen L, Rejto PA, Rose PW, Guzman MC, Dovalsantos EZ, Lee S, McGee K, Mohajeri M, Liese A, Tao J, Kosa MB, Liu B, Batugo MR, Gleeson JP, Wu ZP, Liu J, Meador JW 3rd, Ferre RA. Dragovich PS, et al. Among authors: chen l. J Med Chem. 2003 Oct 9;46(21):4572-85. doi: 10.1021/jm030166l. J Med Chem. 2003. PMID: 14521419
Promoting appropriate medication use by leveraging medical big data.
Hong L, Huang S, Cai X, Lin Z, Shao Y, Chen L, Zhao M, Yang C. Hong L, et al. Among authors: chen l. Front Digit Health. 2024 Nov 7;6:1198904. doi: 10.3389/fdgth.2024.1198904. eCollection 2024. Front Digit Health. 2024. PMID: 39575413 Free PMC article.
Lenvatinib, sintilimab combined interventional treatment vs bevacizumab, sintilimab combined interventional treatment for intermediate-advanced unresectable hepatocellular carcinoma.
Han RY, Gan LJ, Lang MR, Ren SH, Liu DM, Li GT, Liu YY, Tian XD, Zhu KW, Sun LY, Chen L, Song TQ. Han RY, et al. Among authors: chen l. World J Gastroenterol. 2024 Nov 21;30(43):4620-4635. doi: 10.3748/wjg.v30.i43.4620. World J Gastroenterol. 2024. PMID: 39575400 Free PMC article.
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