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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
Grefhorst A, Elzinga BM, Voshol PJ, Plösch T, Kok T, Bloks VW, van der Sluijs FH, Havekes LM, Romijn JA, Verkade HJ, Kuipers F. Grefhorst A, et al. Among authors: plosch t. J Biol Chem. 2002 Sep 13;277(37):34182-90. doi: 10.1074/jbc.M204887200. Epub 2002 Jul 3. J Biol Chem. 2002. PMID: 12097330 Free article.
Hyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient mice.
Bloks VW, Plösch T, van Goor H, Roelofsen H, Baller J, Havinga R, Verkade HJ, van Tol A, Jansen PL, Kuipers F. Bloks VW, et al. Among authors: plosch t. J Lipid Res. 2001 Jan;42(1):41-50. J Lipid Res. 2001. PMID: 11160364 Free article.
Distinct atherosclerotic lesions were found in aged fch/fch mice.Thus, ferrochelatase deficiency in mice leads to liver disease associated with altered hepatic lipid metabolism, a characteristic hyperlipidemia, and development of atherosclerosis.-Bloks, V. W., T. Plosch
Distinct atherosclerotic lesions were found in aged fch/fch mice.Thus, ferrochelatase deficiency in mice leads to liver disease associated w …
116 results