Clifford SC - Search Results

1

Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.

Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER. Zatyka M, et al. Among authors: clifford sc. Cancer Res. 2002 Jul 1;62(13):3803-11. Cancer Res. 2002. PMID: 12097293

2

Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

Clifford SC, Prowse AH, Affara NA, Buys CH, Maher ER. Clifford SC, et al. Genes Chromosomes Cancer. 1998 Jul;22(3):200-9. doi: 10.1002/(sici)1098-2264(199807)22:3<200::aid-gcc5>3.0.co;2-#. Genes Chromosomes Cancer. 1998. PMID: 9624531

3

Hepatocyte growth factor-stimulated renal tubular mitogenesis: effects on expression of c-myc, c-fos, c-met, VEGF and the VHL tumour-suppressor and related genes.

Clifford SC, Czapla K, Richards FM, O'Donoghue DJ, Maher ER. Clifford SC, et al. Br J Cancer. 1998 May;77(9):1420-8. doi: 10.1038/bjc.1998.235. Br J Cancer. 1998. PMID: 9652757 Free PMC article.

4

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. Maxwell PH, et al. Among authors: clifford sc. Nature. 1999 May 20;399(6733):271-5. doi: 10.1038/20459. Nature. 1999. PMID: 10353251

5

Genomic organization and chromosomal localization of the human CUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development.

Clifford SC, Walsh S, Hewson K, Green EK, Brinke A, Green PM, Gianelli F, Eng C, Maher ER. Clifford SC, et al. Genes Chromosomes Cancer. 1999 Sep;26(1):20-8. Genes Chromosomes Cancer. 1999. PMID: 10441001

6

Differences in allelic distribution of two polymorphisms in the VHL-associated gene CUL2 in pheochromocytoma patients without somatic CUL2 mutations.

Duerr EM, Gimm O, Neuberg DS, Kum JB, Clifford SC, Toledo SP, Maher ER, Dahia PL, Eng C. Duerr EM, et al. Among authors: clifford sc. J Clin Endocrinol Metab. 1999 Sep;84(9):3207-11. doi: 10.1210/jcem.84.9.5961. J Clin Endocrinol Metab. 1999. PMID: 10487688

7

Familial clear cell renal cell carcinoma (FCRC): clinical features and mutation analysis of the VHL, MET, and CUL2 candidate genes.

Woodward ER, Clifford SC, Astuti D, Affara NA, Maher ER. Woodward ER, et al. Among authors: clifford sc. J Med Genet. 2000 May;37(5):348-53. doi: 10.1136/jmg.37.5.348. J Med Genet. 2000. PMID: 10807693 Free PMC article.

8

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH. Cockman ME, et al. Among authors: clifford sc. J Biol Chem. 2000 Aug 18;275(33):25733-41. doi: 10.1074/jbc.M002740200. J Biol Chem. 2000. PMID: 10823831 Free article.

9

Comparative sequence analysis of the VHL tumor suppressor gene.

Woodward ER, Buchberger A, Clifford SC, Hurst LD, Affara NA, Maher ER. Woodward ER, et al. Among authors: clifford sc. Genomics. 2000 May 1;65(3):253-65. doi: 10.1006/geno.2000.6144. Genomics. 2000. PMID: 10857749

10

Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER. Clifford SC, et al. Hum Mol Genet. 2001 May 1;10(10):1029-38. doi: 10.1093/hmg/10.10.1029. Hum Mol Genet. 2001. PMID: 11331613

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