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Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.
Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O. Cui S, et al. Among authors: tanabe o. Mol Cell Biol. 2011 Aug;31(16):3298-311. doi: 10.1128/MCB.05310-11. Epub 2011 Jun 13. Mol Cell Biol. 2011. PMID: 21670149 Free PMC article.
Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes.
Campbell AD, Cui S, Shi L, Urbonya R, Mathias A, Bradley K, Bonsu KO, Douglas RR, Halford B, Schmidt L, Harro D, Giacherio D, Tanimoto K, Tanabe O, Engel JD. Campbell AD, et al. Among authors: tanabe o. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18808-13. doi: 10.1073/pnas.1104964108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042865 Free PMC article.
TRIM28 is essential for erythroblast differentiation in the mouse.
Hosoya T, Clifford M, Losson R, Tanabe O, Engel JD. Hosoya T, et al. Among authors: tanabe o. Blood. 2013 Nov 28;122(23):3798-807. doi: 10.1182/blood-2013-04-496166. Epub 2013 Oct 3. Blood. 2013. PMID: 24092935 Free PMC article.
103 results