Fraser P - Search Results

1

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC. Fukami S, et al. Among authors: fraser p. Neurosci Res. 2002 May;43(1):39-56. doi: 10.1016/s0168-0102(02)00015-9. Neurosci Res. 2002. PMID: 12074840

2

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice.

Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ. Citron M, et al. Among authors: fraser p. Nat Med. 1997 Jan;3(1):67-72. doi: 10.1038/nm0197-67. Nat Med. 1997. PMID: 8986743

3

Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease.

Ishii K, Tamaoka A, Mizusawa H, Shoji S, Ohtake T, Fraser PE, Takahashi H, Tsuji S, Gearing M, Mizutani T, Yamada S, Kato M, St George-Hyslop PH, Mirra SS, Mori H. Ishii K, et al. Among authors: fraser pe. Brain Res. 1997 Feb 14;748(1-2):250-2. doi: 10.1016/s0006-8993(96)01363-7. Brain Res. 1997. PMID: 9067471

4

Two homologous genes causing early-onset familial Alzheimer's disease.

St George-Hyslop PH, Levesque G, Levesque L, Rommens J, Westaway D, Fraser PE. St George-Hyslop PH, et al. Among authors: fraser pe. Cold Spring Harb Symp Quant Biol. 1996;61:559-64. Cold Spring Harb Symp Quant Biol. 1996. PMID: 9246482 No abstract available.

5

Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.

Tamaoka A, Fraser PE, Ishii K, Sahara N, Ozawa K, Ikeda M, Saunders AM, Komatsuzaki Y, Sherrington R, Levesque G, Yu G, Rogaeva E, Shoji S, Nee LE, Pollen DA, Hendriks L, Martin JJ, Van Broeckhoven C, Roses AD, Farrer LA, St George-Hyslop PH, Mori H. Tamaoka A, et al. Among authors: fraser pe. Brain Res Mol Brain Res. 1998 May;56(1-2):178-85. doi: 10.1016/s0169-328x(98)00044-8. Brain Res Mol Brain Res. 1998. PMID: 9602117 Free article.

6

Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1.

Lévesque L, Annaert W, Craessaerts K, Mathews PM, Seeger M, Nixon RA, Van Leuven F, Gandy S, Westaway D, St George-Hyslop P, De Strooper B, Fraser PE. Lévesque L, et al. Among authors: fraser pe. Mol Med. 1999 Aug;5(8):542-54. Mol Med. 1999. PMID: 10501657 Free PMC article.

7

Glial expression of presenilin epitopes in human brain with cerebral infarction and in astrocytoma.

Miake H, Tsuchiya K, Nakamura A, Ikeda K, Levesque L, Fraser PE, St-George Hyslop PH, Mizusawa H, Uchihara T. Miake H, et al. Among authors: fraser pe. Acta Neuropathol. 1999 Oct;98(4):337-40. doi: 10.1007/s004010051090. Acta Neuropathol. 1999. PMID: 10502036

8

Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons.

Annaert WG, Levesque L, Craessaerts K, Dierinck I, Snellings G, Westaway D, George-Hyslop PS, Cordell B, Fraser P, De Strooper B. Annaert WG, et al. Among authors: fraser p. J Cell Biol. 1999 Oct 18;147(2):277-94. doi: 10.1083/jcb.147.2.277. J Cell Biol. 1999. PMID: 10525535 Free PMC article.

9

Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.

Verdile G, Martins RN, Duthie M, Holmes E, St George-Hyslop PH, Fraser PE. Verdile G, et al. Among authors: fraser pe. J Biol Chem. 2000 Jul 7;275(27):20794-8. doi: 10.1074/jbc.C000208200. J Biol Chem. 2000. PMID: 10801777 Free article.

10

Presenilin structure, function and role in Alzheimer disease.

Fraser PE, Yang DS, Yu G, Lévesque L, Nishimura M, Arawaka S, Serpell LC, Rogaeva E, St George-Hyslop P. Fraser PE, et al. Biochim Biophys Acta. 2000 Jul 26;1502(1):1-15. doi: 10.1016/s0925-4439(00)00028-4. Biochim Biophys Acta. 2000. PMID: 10899427 Free article. Review.

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