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Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E. Myers JW, et al. Among authors: park wy. bioRxiv [Preprint]. 2024 Nov 1:2024.10.28.620705. doi: 10.1101/2024.10.28.620705. bioRxiv. 2024. PMID: 39553975 Free PMC article. Preprint.
Impact of ciprofloxacin with autophagy on renal tubular injury.
Park WY, Lim SH, Kim Y, Paek JH, Jin K, Han S, Ahn KS, Lee J. Park WY, et al. Medicine (Baltimore). 2024 Oct 4;103(40):e39888. doi: 10.1097/MD.0000000000039888. Medicine (Baltimore). 2024. PMID: 39465743 Free PMC article.
Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome.
Park S, Kim S, Kim B, Kim DS, Kim J, Ahn Y, Kim H, Song M, Shim I, Jung SH, Cho C, Lim S, Hong S, Jo H, Fahed AC, Natarajan P, Ellinor PT, Torkamani A, Park WY, Yu TY, Myung W, Won HH. Park S, et al. Among authors: park wy. Nat Genet. 2024 Nov;56(11):2380-2391. doi: 10.1038/s41588-024-01933-1. Epub 2024 Sep 30. Nat Genet. 2024. PMID: 39349817 Free PMC article.
Therapeutic single-cell landscape: methotrexate exacerbates interstitial lung disease by compromising the stemness of alveolar epithelial cells under systemic inflammation.
Chang SH, Jung S, Chae JJ, Kim JY, Kim SU, Choi JY, Han HJ, Kim HT, Kim HJ, Kim HJ, Park WY, Sparks JA, Lee EY, Lee JS. Chang SH, et al. Among authors: park wy. EBioMedicine. 2024 Oct;108:105339. doi: 10.1016/j.ebiom.2024.105339. Epub 2024 Sep 19. EBioMedicine. 2024. PMID: 39303666 Free PMC article.
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis.
Pinette JA, Myers JW, Park WY, Bryant HG, Eddie AM, Wilson GA, Montufar C, Shaikh Z, Vue Z, Nunn ER, Bessho R, Cottam MA, Haase VH, Hinton AO, Spinelli JB, Cartailler JP, Zaganjor E. Pinette JA, et al. Among authors: park wy. J Lipid Res. 2024 Oct;65(10):100641. doi: 10.1016/j.jlr.2024.100641. Epub 2024 Sep 6. J Lipid Res. 2024. PMID: 39245323 Free article.
703 results