Zeng Y - Search Results

1

Synthesis of N-[4-[1-ethyl-2-(2,4-diaminofuro[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid as an antifolate.

Gangjee A, Zeng Y, McGuire JJ, Kisliuk RL. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2002 Apr 25;45(9):1942-8. doi: 10.1021/jm010575m. J Med Chem. 2002. PMID: 11960504

2

Synthesis of classical and nonclassical, partially restricted, linear, tricyclic 5-deaza antifolates.

Gangjee A, Zeng Y, McGuire JJ, Kisliuk RL. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2002 Nov 7;45(23):5173-81. doi: 10.1021/jm0202369. J Med Chem. 2002. PMID: 12408727

3

Recent advances in the chemistry and biology of folypoly-gamma-glutamate synthetase substrates and inhibitors.

Gangjee A, Dubash NP, Zeng Y, McGuire JJ. Gangjee A, et al. Among authors: zeng y. Curr Med Chem Anticancer Agents. 2002 May;2(3):331-55. doi: 10.2174/1568011024606352. Curr Med Chem Anticancer Agents. 2002. PMID: 12678736 Review.

4

Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

Gangjee A, Zeng Y, McGuire JJ, Mehraein F, Kisliuk RL. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2004 Dec 30;47(27):6893-901. doi: 10.1021/jm040123k. J Med Chem. 2004. PMID: 15615538

5

Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity.

Gangjee A, Zeng Y, Ihnat M, Warnke LA, Green DW, Kisliuk RL, Lin FT. Gangjee A, et al. Among authors: zeng y. Bioorg Med Chem. 2005 Sep 15;13(18):5475-91. doi: 10.1016/j.bmc.2005.04.087. Bioorg Med Chem. 2005. PMID: 16039863

6

Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

Gangjee A, Zeng Y, McGuire JJ, Kisliuk RL. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2005 Aug 11;48(16):5329-36. doi: 10.1021/jm058213s. J Med Chem. 2005. PMID: 16078850 Free PMC article.

7

Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as antifolates.

Gangjee A, Zeng Y, Talreja T, McGuire JJ, Kisliuk RL, Queener SF. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2007 Jun 28;50(13):3046-53. doi: 10.1021/jm070165j. Epub 2007 Jun 7. J Med Chem. 2007. PMID: 17552508 Free PMC article.

8

Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.

Gangjee A, Li W, Lin L, Zeng Y, Ihnat M, Warnke LA, Green DW, Cody V, Pace J, Queener SF. Gangjee A, et al. Among authors: zeng y. Bioorg Med Chem. 2009 Oct 15;17(20):7324-36. doi: 10.1016/j.bmc.2009.08.044. Epub 2009 Aug 22. Bioorg Med Chem. 2009. PMID: 19748785 Free PMC article.

9

Effect of C9-methyl substitution and C8-C9 conformational restriction on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines.

Gangjee A, Zeng Y, McGuire JJ, Kisliuk RL. Gangjee A, et al. Among authors: zeng y. J Med Chem. 2000 Aug 10;43(16):3125-33. doi: 10.1021/jm000130i. J Med Chem. 2000. PMID: 10956221

10

Inhibition of insulin-like growth factor I receptor autophosphorylation by novel 6-5 ring-fused compounds.

Li W, Favelyukis S, Yang J, Zeng Y, Yu J, Gangjee A, Miller WT. Li W, et al. Among authors: zeng y. Biochem Pharmacol. 2004 Jul 1;68(1):145-54. doi: 10.1016/j.bcp.2004.03.013. Biochem Pharmacol. 2004. PMID: 15183126

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