Thinakaran G - Search Results

1

Presenilin 1 is required for maturation and cell surface accumulation of nicastrin.

Leem JY, Vijayan S, Han P, Cai D, Machura M, Lopes KO, Veselits ML, Xu H, Thinakaran G. Leem JY, et al. Among authors: thinakaran g. J Biol Chem. 2002 May 24;277(21):19236-40. doi: 10.1074/jbc.C200148200. Epub 2002 Apr 9. J Biol Chem. 2002. PMID: 11943765 Free article.

2

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.

Thinakaran G, Teplow DB, Siman R, Greenberg B, Sisodia SS. Thinakaran G, et al. J Biol Chem. 1996 Apr 19;271(16):9390-7. doi: 10.1074/jbc.271.16.9390. J Biol Chem. 1996. PMID: 8621605 Free article.

3

Endoproteolytic processing and stabilization of wild-type and mutant presenilin.

Ratovitski T, Slunt HH, Thinakaran G, Price DL, Sisodia SS, Borchelt DR. Ratovitski T, et al. Among authors: thinakaran g. J Biol Chem. 1997 Sep 26;272(39):24536-41. doi: 10.1074/jbc.272.39.24536. J Biol Chem. 1997. PMID: 9305918 Free article.

4

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

Thinakaran G, Harris CL, Ratovitski T, Davenport F, Slunt HH, Price DL, Borchelt DR, Sisodia SS. Thinakaran G, et al. J Biol Chem. 1997 Nov 7;272(45):28415-22. doi: 10.1074/jbc.272.45.28415. J Biol Chem. 1997. PMID: 9353300 Free article.

5

Effects of PS1 deficiency on membrane protein trafficking in neurons.

Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, Sisodia SS. Naruse S, et al. Among authors: thinakaran g. Neuron. 1998 Nov;21(5):1213-21. doi: 10.1016/s0896-6273(00)80637-6. Neuron. 1998. PMID: 9856475 Free article.

6

Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.

Saura CA, Tomita T, Davenport F, Harris CL, Iwatsubo T, Thinakaran G. Saura CA, et al. Among authors: thinakaran g. J Biol Chem. 1999 May 14;274(20):13818-23. doi: 10.1074/jbc.274.20.13818. J Biol Chem. 1999. PMID: 10318786 Free article.

7

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

Saura CA, Tomita T, Soriano S, Takahashi M, Leem JY, Honda T, Koo EH, Iwatsubo T, Thinakaran G. Saura CA, et al. Among authors: thinakaran g. J Biol Chem. 2000 Jun 2;275(22):17136-42. doi: 10.1074/jbc.M909624199. J Biol Chem. 2000. PMID: 10748144 Free article.

8

Subcellular localization of presenilins: association with a unique membrane pool in cultured cells.

Kim SH, Lah JJ, Thinakaran G, Levey A, Sisodia SS. Kim SH, et al. Among authors: thinakaran g. Neurobiol Dis. 2000 Apr;7(2):99-117. doi: 10.1006/nbdi.1999.0280. Neurobiol Dis. 2000. PMID: 10783294

9

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G. Sato N, et al. Among authors: thinakaran g. Nat Cell Biol. 2000 Dec;2(12):863-70. doi: 10.1038/35046500. Nat Cell Biol. 2000. PMID: 11146649

10

Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.

Kim SH, Leem JY, Lah JJ, Slunt HH, Levey AI, Thinakaran G, Sisodia SS. Kim SH, et al. Among authors: thinakaran g. J Biol Chem. 2001 Nov 16;276(46):43343-50. doi: 10.1074/jbc.M108245200. Epub 2001 Sep 19. J Biol Chem. 2001. PMID: 11564743 Free article.

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