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Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma.
Takahashi N, Kawada T, Yamamoto T, Goto T, Taimatsu A, Aoki N, Kawasaki H, Taira K, Yokoyama KK, Kamei Y, Fushiki T. Takahashi N, et al. Among authors: kawada t. J Biol Chem. 2002 May 10;277(19):16906-12. doi: 10.1074/jbc.M200585200. Epub 2002 Mar 7. J Biol Chem. 2002. PMID: 11884404 Free article.
Abietic acid activates peroxisome proliferator-activated receptor-gamma (PPARgamma) in RAW264.7 macrophages and 3T3-L1 adipocytes to regulate gene expression involved in inflammation and lipid metabolism.
Takahashi N, Kawada T, Goto T, Kim CS, Taimatsu A, Egawa K, Yamamoto T, Jisaka M, Nishimura K, Yokota K, Yu R, Fushiki T. Takahashi N, et al. Among authors: kawada t. FEBS Lett. 2003 Aug 28;550(1-3):190-4. doi: 10.1016/s0014-5793(03)00859-7. FEBS Lett. 2003. PMID: 12935909 Free article.
Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.
Goto T, Takahashi N, Kato S, Egawa K, Ebisu S, Moriyama T, Fushiki T, Kawada T. Goto T, et al. Among authors: kawada t. Biochem Biophys Res Commun. 2005 Nov 18;337(2):440-5. doi: 10.1016/j.bbrc.2005.09.077. Epub 2005 Sep 21. Biochem Biophys Res Commun. 2005. PMID: 16202384
Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.
Takahashi N, Goto T, Taimatsu A, Egawa K, Katoh S, Kusudo T, Sakamoto T, Ohyane C, Lee JY, Kim YI, Uemura T, Hirai S, Kawada T. Takahashi N, et al. Among authors: kawada t. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1372-6. doi: 10.1016/j.bbrc.2009.10.162. Epub 2009 Nov 3. Biochem Biophys Res Commun. 2009. PMID: 19891958
2,166 results