Schoeberl B - Search Results

1

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors.

Schoeberl B, Eichler-Jonsson C, Gilles ED, Müller G. Schoeberl B, et al. Nat Biotechnol. 2002 Apr;20(4):370-5. doi: 10.1038/nbt0402-370. Nat Biotechnol. 2002. PMID: 11923843

2

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data.

Chen WW, Schoeberl B, Jasper PJ, Niepel M, Nielsen UB, Lauffenburger DA, Sorger PK. Chen WW, et al. Among authors: schoeberl b. Mol Syst Biol. 2009;5:239. doi: 10.1038/msb.2008.74. Epub 2009 Jan 20. Mol Syst Biol. 2009. PMID: 19156131 Free PMC article.

3

Competing docking interactions can bring about bistability in the MAPK cascade.

Legewie S, Schoeberl B, Blüthgen N, Herzel H. Legewie S, et al. Among authors: schoeberl b. Biophys J. 2007 Oct 1;93(7):2279-88. doi: 10.1529/biophysj.107.109132. Epub 2007 May 25. Biophys J. 2007. PMID: 17526574 Free PMC article.

4

A data-driven computational model of the ErbB receptor signaling network.

Schoeberl B, Pace E, Howard S, Garantcharova V, Kudla A, Sorger PK, Nielsen UB. Schoeberl B, et al. Conf Proc IEEE Eng Med Biol Soc. 2006;2006:53-4. doi: 10.1109/IEMBS.2006.259754. Conf Proc IEEE Eng Med Biol Soc. 2006. PMID: 17946779

5

Control of MAPK signalling: from complexity to what really matters.

Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R, Westerhoff HV. Hornberg JJ, et al. Among authors: schoeberl b. Oncogene. 2005 Aug 25;24(36):5533-42. doi: 10.1038/sj.onc.1208817. Oncogene. 2005. PMID: 16007170

6

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer.

Seigal A, Beguerisse-Díaz M, Schoeberl B, Niepel M, Harrington HA. Seigal A, et al. Among authors: schoeberl b. J R Soc Interface. 2019 Feb 28;16(151):20180661. doi: 10.1098/rsif.2018.0661. J R Soc Interface. 2019. PMID: 30958184 Free PMC article.

7

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.

Sheng Q, Liu X, Fleming E, Yuan K, Piao H, Chen J, Moustafa Z, Thomas RK, Greulich H, Schinzel A, Zaghlul S, Batt D, Ettenberg S, Meyerson M, Schoeberl B, Kung AL, Hahn WC, Drapkin R, Livingston DM, Liu JF. Sheng Q, et al. Among authors: schoeberl b. Cancer Cell. 2010 Mar 16;17(3):298-310. doi: 10.1016/j.ccr.2009.12.047. Cancer Cell. 2010. PMID: 20227043 Free PMC article.

8

Systems biology and combination therapy in the quest for clinical efficacy.

Fitzgerald JB, Schoeberl B, Nielsen UB, Sorger PK. Fitzgerald JB, et al. Among authors: schoeberl b. Nat Chem Biol. 2006 Sep;2(9):458-66. doi: 10.1038/nchembio817. Nat Chem Biol. 2006. PMID: 16921358

9

Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.

Schoeberl B, Pace EA, Fitzgerald JB, Harms BD, Xu L, Nie L, Linggi B, Kalra A, Paragas V, Bukhalid R, Grantcharova V, Kohli N, West KA, Leszczyniecka M, Feldhaus MJ, Kudla AJ, Nielsen UB. Schoeberl B, et al. Sci Signal. 2009 Jun 30;2(77):ra31. doi: 10.1126/scisignal.2000352. Sci Signal. 2009. PMID: 19567914

10

Optimizing properties of antireceptor antibodies using kinetic computational models and experiments.

Harms BD, Kearns JD, Su SV, Kohli N, Nielsen UB, Schoeberl B. Harms BD, et al. Among authors: schoeberl b. Methods Enzymol. 2012;502:67-87. doi: 10.1016/B978-0-12-416039-2.00004-5. Methods Enzymol. 2012. PMID: 22208982

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