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Page 1
Nanobodies and their Use in GPCR Drug Discovery.
Cromie KD, Van Heeke G, Boutton C. Cromie KD, et al. Curr Top Med Chem. 2015;15(24):2543-57. doi: 10.2174/1568026615666150701113549. Curr Top Med Chem. 2015. PMID: 26126902 Review.
Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction.
Huet HA, Growney JD, Johnson JA, Li J, Bilic S, Ostrom L, Zafari M, Kowal C, Yang G, Royo A, Jensen M, Dombrecht B, Meerschaert KR, Kolkman JA, Cromie KD, Mosher R, Gao H, Schuller A, Isaacs R, Sellers WR, Ettenberg SA. Huet HA, et al. Among authors: cromie kd. MAbs. 2014;6(6):1560-70. doi: 10.4161/19420862.2014.975099. MAbs. 2014. PMID: 25484045 Free PMC article.
Potent and efficacious inhibition of CXCR2 signaling by biparatopic nanobodies combining two distinct modes of action.
Bradley ME, Dombrecht B, Manini J, Willis J, Vlerick D, De Taeye S, Van den Heede K, Roobrouck A, Grot E, Kent TC, Laeremans T, Steffensen S, Van Heeke G, Brown Z, Charlton SJ, Cromie KD. Bradley ME, et al. Among authors: cromie kd. Mol Pharmacol. 2015 Feb;87(2):251-62. doi: 10.1124/mol.114.094821. Epub 2014 Dec 2. Mol Pharmacol. 2015. PMID: 25468882
Penicillin-binding proteins of gram-negative bacteria.
Spratt BG, Cromie KD. Spratt BG, et al. Among authors: cromie kd. Rev Infect Dis. 1988 Jul-Aug;10(4):699-711. doi: 10.1093/clinids/10.4.699. Rev Infect Dis. 1988. PMID: 3055170 Review.