Cappai R - Search Results

1

Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein.

White AR, Multhaup G, Galatis D, McKinstry WJ, Parker MW, Pipkorn R, Beyreuther K, Masters CL, Cappai R. White AR, et al. Among authors: cappai r. J Neurosci. 2002 Jan 15;22(2):365-76. doi: 10.1523/JNEUROSCI.22-02-00365.2002. J Neurosci. 2002. PMID: 11784781 Free PMC article.

2

Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).

Hamilton JA, Whitty G, White AR, Jobling MF, Thompson A, Barrow CJ, Cappai R, Beyreuther K, Masters CL. Hamilton JA, et al. Among authors: cappai r. Brain Res. 2002 Jun 14;940(1-2):49-54. doi: 10.1016/s0006-8993(02)02589-1. Brain Res. 2002. PMID: 12020874

3

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.

Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX. Maynard CJ, et al. Among authors: cappai r. J Biol Chem. 2002 Nov 22;277(47):44670-6. doi: 10.1074/jbc.M204379200. Epub 2002 Sep 4. J Biol Chem. 2002. PMID: 12215434 Free article.

4

Neurotoxicity from glutathione depletion is dependent on extracellular trace copper.

White AR, Cappai R. White AR, et al. Among authors: cappai r. J Neurosci Res. 2003 Mar 15;71(6):889-97. doi: 10.1002/jnr.10537. J Neurosci Res. 2003. PMID: 12605416

5

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.

Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. Barnham KJ, et al. Among authors: cappai r. J Biol Chem. 2003 May 9;278(19):17401-7. doi: 10.1074/jbc.M300629200. Epub 2003 Feb 28. J Biol Chem. 2003. PMID: 12611883 Free article.

6

Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.

White AR, Maher F, Brazier MW, Jobling MF, Thyer J, Stewart LR, Thompson A, Gibson R, Masters CL, Multhaup G, Beyreuther K, Barrow CJ, Collins SJ, Cappai R. White AR, et al. Among authors: cappai r. Brain Res. 2003 Mar 21;966(2):231-44. doi: 10.1016/s0006-8993(02)04173-2. Brain Res. 2003. PMID: 12618346

7

Iron inhibits neurotoxicity induced by trace copper and biological reductants.

White AR, Barnham KJ, Huang X, Voltakis I, Beyreuther K, Masters CL, Cherny RA, Bush AI, Cappai R. White AR, et al. Among authors: cappai r. J Biol Inorg Chem. 2004 Apr;9(3):269-80. doi: 10.1007/s00775-004-0521-8. Epub 2004 Feb 3. J Biol Inorg Chem. 2004. PMID: 14758525

8

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.

Bellingham SA, Ciccotosto GD, Needham BE, Fodero LR, White AR, Masters CL, Cappai R, Camakaris J. Bellingham SA, et al. Among authors: cappai r. J Neurochem. 2004 Oct;91(2):423-8. doi: 10.1111/j.1471-4159.2004.02731.x. J Neurochem. 2004. PMID: 15447675 Free article.

9

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

Crouch PJ, Blake R, Duce JA, Ciccotosto GD, Li QX, Barnham KJ, Curtain CC, Cherny RA, Cappai R, Dyrks T, Masters CL, Trounce IA. Crouch PJ, et al. Among authors: cappai r. J Neurosci. 2005 Jan 19;25(3):672-9. doi: 10.1523/JNEUROSCI.4276-04.2005. J Neurosci. 2005. PMID: 15659604 Free PMC article.

10

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.

Cappai R, Cheng F, Ciccotosto GD, Needham BE, Masters CL, Multhaup G, Fransson LA, Mani K. Cappai R, et al. J Biol Chem. 2005 Apr 8;280(14):13913-20. doi: 10.1074/jbc.M409179200. Epub 2005 Jan 27. J Biol Chem. 2005. PMID: 15677459 Free article.

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