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Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production.
Grefhorst A, Hoekstra J, Derks TG, Ouwens DM, Baller JF, Havinga R, Havekes LM, Romijn JA, Kuipers F. Grefhorst A, et al. Among authors: havekes lm. Am J Physiol Gastrointest Liver Physiol. 2005 Sep;289(3):G592-8. doi: 10.1152/ajpgi.00063.2005. Epub 2005 Apr 7. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15817811 Free article.
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
Grefhorst A, Elzinga BM, Voshol PJ, Plösch T, Kok T, Bloks VW, van der Sluijs FH, Havekes LM, Romijn JA, Verkade HJ, Kuipers F. Grefhorst A, et al. Among authors: havekes lm. J Biol Chem. 2002 Sep 13;277(37):34182-90. doi: 10.1074/jbc.M204887200. Epub 2002 Jul 3. J Biol Chem. 2002. PMID: 12097330 Free article.
Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion.
Mensenkamp AR, Teusink B, Baller JF, Wolters H, Havinga R, van Dijk KW, Havekes LM, Kuipers F. Mensenkamp AR, et al. Among authors: havekes lm. Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1366-72. doi: 10.1161/hq0801.093864. Arterioscler Thromb Vasc Biol. 2001. PMID: 11498467
GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE*3-Leiden mice.
Parlevliet ET, Wang Y, Geerling JJ, Schröder-Van der Elst JP, Picha K, O'Neil K, Stojanovic-Susulic V, Ort T, Havekes LM, Romijn JA, Pijl H, Rensen PC. Parlevliet ET, et al. Among authors: havekes lm. PLoS One. 2012;7(11):e49152. doi: 10.1371/journal.pone.0049152. Epub 2012 Nov 2. PLoS One. 2012. PMID: 23133675 Free PMC article.
448 results