Field SJ - Search Results

1

The E2F1-3 transcription factors are essential for cellular proliferation.

Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: field sj. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808

2

Myc requires distinct E2F activities to induce S phase and apoptosis.

Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR. Leone G, et al. Among authors: field sj. Mol Cell. 2001 Jul;8(1):105-13. doi: 10.1016/s1097-2765(01)00275-1. Mol Cell. 2001. PMID: 11511364 Free article.

3

E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.

Zhu JW, Field SJ, Gore L, Thompson M, Yang H, Fujiwara Y, Cardiff RD, Greenberg M, Orkin SH, DeGregori J. Zhu JW, et al. Among authors: field sj. Mol Cell Biol. 2001 Dec;21(24):8547-64. doi: 10.1128/MCB.21.24.8547-8564.2001. Mol Cell Biol. 2001. PMID: 11713289 Free PMC article.

4

Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity.

Murga M, Fernández-Capetillo O, Field SJ, Moreno B, Borlado LR, Fujiwara Y, Balomenos D, Vicario A, Carrera AC, Orkin SH, Greenberg ME, Zubiaga AM. Murga M, et al. Among authors: field sj. Immunity. 2001 Dec;15(6):959-70. doi: 10.1016/s1074-7613(01)00254-0. Immunity. 2001. PMID: 11754817 Free article.

5

E2F-1 functions in mice to promote apoptosis and suppress proliferation.

Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG Jr, Livingston DM, Orkin SH, Greenberg ME. Field SJ, et al. Cell. 1996 May 17;85(4):549-61. doi: 10.1016/s0092-8674(00)81255-6. Cell. 1996. PMID: 8653790 Free article.

6

Growth and differentiation of embryonic stem cells that lack an intact c-fos gene.

Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Spiegelman BM, Greenberg ME. Field SJ, et al. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9306-10. doi: 10.1073/pnas.89.19.9306. Proc Natl Acad Sci U S A. 1992. PMID: 1329091 Free PMC article.

7

Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice.

Iglesias A, Murga M, Laresgoiti U, Skoudy A, Bernales I, Fullaondo A, Moreno B, Lloreta J, Field SJ, Real FX, Zubiaga AM. Iglesias A, et al. Among authors: field sj. J Clin Invest. 2004 May;113(10):1398-407. doi: 10.1172/JCI18879. J Clin Invest. 2004. PMID: 15146237 Free PMC article.

8

Accelerated DNA replication in E2F1- and E2F2-deficient macrophages leads to induction of the DNA damage response and p21(CIP1)-dependent senescence.

Iglesias-Ara A, Zenarruzabeitia O, Fernandez-Rueda J, Sánchez-Tilló E, Field SJ, Celada A, Zubiaga AM. Iglesias-Ara A, et al. Among authors: field sj. Oncogene. 2010 Oct 14;29(41):5579-90. doi: 10.1038/onc.2010.296. Epub 2010 Aug 2. Oncogene. 2010. PMID: 20676136

9

A role for E2F1 in the induction of apoptosis during thymic negative selection.

García I, Murga M, Vicario A, Field SJ, Zubiaga AM. García I, et al. Among authors: field sj. Cell Growth Differ. 2000 Feb;11(2):91-8. Cell Growth Differ. 2000. PMID: 10714765

10

E2F2 represses cell cycle regulators to maintain quiescence.

Infante A, Laresgoiti U, Fernández-Rueda J, Fullaondo A, Galán J, Díaz-Uriarte R, Malumbres M, Field SJ, Zubiaga AM. Infante A, et al. Among authors: field sj. Cell Cycle. 2008 Dec 15;7(24):3915-27. doi: 10.4161/cc.7.24.7379. Epub 2008 Dec 10. Cell Cycle. 2008. PMID: 19066456

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