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Practical preclinical model for assessing the potential for unconjugated hyperbilirubinemia produced by human immunodeficiency virus protease inhibitors.
Kempf DJ, Waring JF, Morfitt DC, Werner P, Ebert B, Mitten M, Nguyen B, Randolph JT, DeGoey DA, Klein LL, Marsh K. Kempf DJ, et al. Among authors: morfitt dc. Antimicrob Agents Chemother. 2006 Feb;50(2):762-4. doi: 10.1128/AAC.50.2.762-764.2006. Antimicrob Agents Chemother. 2006. PMID: 16436740 Free PMC article.
2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.
Degoey DA, Grampovnik DJ, Flentge CA, Flosi WJ, Chen HJ, Yeung CM, Randolph JT, Klein LL, Dekhtyar T, Colletti L, Marsh KC, Stoll V, Mamo M, Morfitt DC, Nguyen B, Schmidt JM, Swanson SJ, Mo H, Kati WM, Molla A, Kempf DJ. Degoey DA, et al. Among authors: morfitt dc. J Med Chem. 2009 Apr 23;52(8):2571-86. doi: 10.1021/jm900044w. J Med Chem. 2009. PMID: 19323562
14 results