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The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.
Billon-Galés A, Fontaine C, Filipe C, Douin-Echinard V, Fouque MJ, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal JF. Billon-Galés A, et al. Among authors: fouque mj. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):2053-8. doi: 10.1073/pnas.0808742106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188600 Free PMC article.
Stromal estrogen receptor-α promotes tumor growth by normalizing an increased angiogenesis.
Péqueux C, Raymond-Letron I, Blacher S, Boudou F, Adlanmerini M, Fouque MJ, Rochaix P, Noël A, Foidart JM, Krust A, Chambon P, Brouchet L, Arnal JF, Lenfant F. Péqueux C, et al. Among authors: fouque mj. Cancer Res. 2012 Jun 15;72(12):3010-9. doi: 10.1158/0008-5472.CAN-11-3768. Epub 2012 Apr 20. Cancer Res. 2012. PMID: 22523036 Free article.