Scheeren HW - Search Results

1

Molecular clips based on propanediurea: exceptionally high binding affinities for resorcinol guests.

Jansen RJ, de Gelder R, Rowan AE, Scheeren HW, Nolte RJ. Jansen RJ, et al. Among authors: scheeren hw. J Org Chem. 2001 Apr 20;66(8):2643-53. doi: 10.1021/jo001317k. J Org Chem. 2001. PMID: 11304182

2

Semisynthesis of Some 7-Deoxypaclitaxel Analogs from Taxine B.

Wiegerinck PH, Fluks L, Hammink JB, Mulders SJ, de Groot FM, van Rozendaal HL, Scheeren HW. Wiegerinck PH, et al. Among authors: scheeren hw. J Org Chem. 1996 Oct 4;61(20):7092-7100. doi: 10.1021/jo960438a. J Org Chem. 1996. PMID: 11667611

3

Elongated multiple electronic cascade and cyclization spacer systems in activatible anticancer prodrugs for enhanced drug release.

de Groot FM, Loos WJ, Koekkoek R, van Berkom LW, Busscher GF, Seelen AE, Albrecht C, de Bruijn P, Scheeren HW. de Groot FM, et al. Among authors: scheeren hw. J Org Chem. 2001 Dec 28;66(26):8815-30. doi: 10.1021/jo0158884. J Org Chem. 2001. PMID: 11749612

4

Antiviral and antitumor structure-activity relationship studies on tetracyclic eudistomines.

Van Maarseveen JH, Hermkens PH, De Clercq E, Balzarini J, Scheeren HW, Kruse CG. Van Maarseveen JH, et al. Among authors: scheeren hw. J Med Chem. 1992 Aug 21;35(17):3223-30. doi: 10.1021/jm00095a019. J Med Chem. 1992. PMID: 1324318

5

Synthesis and biological activity of beta-glucuronyl carbamate-based prodrugs of paclitaxel as potential candidates for ADEPT.

de Bont DB, Leenders RG, Haisma HJ, van der Meulen-Muileman I, Scheeren HW. de Bont DB, et al. Among authors: scheeren hw. Bioorg Med Chem. 1997 Feb;5(2):405-14. doi: 10.1016/s0968-0896(96)00249-0. Bioorg Med Chem. 1997. PMID: 9061205

6

Novel anthracycline-spacer-beta-glucuronide,-beta-glucoside, and -beta-galactoside prodrugs for application in selective chemotherapy.

Leenders RG, Damen EW, Bijsterveld EJ, Scheeren HW, Houba PH, van der Meulen-Muileman IH, Boven E, Haisma HJ. Leenders RG, et al. Among authors: scheeren hw. Bioorg Med Chem. 1999 Aug;7(8):1597-610. doi: 10.1016/s0968-0896(99)00095-4. Bioorg Med Chem. 1999. PMID: 10482452

7

Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin.

de Groot FM, de Bart AC, Verheijen JH, Scheeren HW. de Groot FM, et al. Among authors: scheeren hw. J Med Chem. 1999 Dec 16;42(25):5277-83. doi: 10.1021/jm9910472. J Med Chem. 1999. PMID: 10602713

8

Paclitaxel esters of malic acid as prodrugs with improved water solubility.

Damen EW, Wiegerinck PH, Braamer L, Sperling D, de Vos D, Scheeren HW. Damen EW, et al. Among authors: scheeren hw. Bioorg Med Chem. 2000 Feb;8(2):427-32. doi: 10.1016/s0968-0896(99)00301-6. Bioorg Med Chem. 2000. PMID: 10722165

9

Synthesis and biological evaluation of 2'-carbamate-linked and 2'-carbonate-linked prodrugs of paclitaxel: selective activation by the tumor-associated protease plasmin.

de Groot FM, van Berkom LW, Scheeren HW. de Groot FM, et al. Among authors: scheeren hw. J Med Chem. 2000 Aug 10;43(16):3093-102. doi: 10.1021/jm0009078. J Med Chem. 2000. PMID: 10956217

10

Anticancer prodrugs for application in monotherapy: targeting hypoxia, tumor-associated enzymes, and receptors.

de Groot FM, Damen EW, Scheeren HW. de Groot FM, et al. Among authors: scheeren hw. Curr Med Chem. 2001 Jul;8(9):1093-122. doi: 10.2174/0929867013372634. Curr Med Chem. 2001. PMID: 11472243 Review.

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