Assem M - Search Results

1

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski MS, Schuetz E. Kuehl P, et al. Among authors: assem m. Nat Genet. 2001 Apr;27(4):383-91. doi: 10.1038/86882. Nat Genet. 2001. PMID: 11279519

2

PharmGKB update: II. CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5.

Schuetz EG, Relling MV, Kishi S, Yang W, Das S, Chen P, Cook EH, Rosner GL, Pui CH, Blanco JG, Edick MJ, Hancock ML, Winick NJ, Dervieux T, Amylon MD, Bash RO, Behm FG, Camitta BM, Raimondi SC, Goh BC, Lee SC, Wang LZ, Fan L, Guo JY, Lamba J, Lim R, Lim HL, Ong AB, Lee HS, Kuehl P, Zhang J, Lin Y, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski MS. Schuetz EG, et al. Among authors: assem m. Pharmacol Rev. 2004 Jun;56(2):159. doi: 10.1124/pr.56.2.1. Pharmacol Rev. 2004. PMID: 15169924 No abstract available.

3

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia.

Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Zhou C, et al. Among authors: assem m. J Clin Invest. 2006 Jun;116(6):1703-12. doi: 10.1172/JCI27793. Epub 2006 May 11. J Clin Invest. 2006. PMID: 16691293 Free PMC article.

4

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

Schuetz EG, Strom S, Yasuda K, Lecureur V, Assem M, Brimer C, Lamba J, Kim RB, Ramachandran V, Komoroski BJ, Venkataramanan R, Cai H, Sinal CJ, Gonzalez FJ, Schuetz JD. Schuetz EG, et al. Among authors: assem m. J Biol Chem. 2001 Oct 19;276(42):39411-8. doi: 10.1074/jbc.M106340200. Epub 2001 Aug 16. J Biol Chem. 2001. PMID: 11509573 Free article.

5

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG. Lamba V, et al. Among authors: assem m. Toxicol Appl Pharmacol. 2004 Sep 15;199(3):251-65. doi: 10.1016/j.taap.2003.12.027. Toxicol Appl Pharmacol. 2004. PMID: 15364541

6

ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics.

Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E. Finkelstein D, et al. Among authors: assem m. Xenobiotica. 2006 Oct-Nov;36(10-11):989-1012. doi: 10.1080/00498250600861769. Xenobiotica. 2006. PMID: 17118917

7

Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences.

Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E. Lamba JK, et al. Among authors: assem m. J Pharmacol Exp Ther. 2004 Nov;311(2):811-21. doi: 10.1124/jpet.104.069310. Epub 2004 Jun 11. J Pharmacol Exp Ther. 2004. PMID: 15194709

8

The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.

Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG. Lin YS, et al. Among authors: assem m. Drug Metab Dispos. 2009 Jun;37(6):1295-304. doi: 10.1124/dmd.108.025213. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251824 Free PMC article.

9

A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression.

Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, Kim RB. Marzolini C, et al. Among authors: assem m. Mol Endocrinol. 2007 Aug;21(8):1769-80. doi: 10.1210/me.2007-0025. Epub 2007 May 22. Mol Endocrinol. 2007. PMID: 17519356

10

Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression.

Pottier N, Cheok MH, Yang W, Assem M, Tracey L, Obenauer JC, Panetta JC, Relling MV, Evans WE. Pottier N, et al. Among authors: assem m. Hum Mol Genet. 2007 Oct 1;16(19):2261-71. doi: 10.1093/hmg/ddm178. Epub 2007 Jul 5. Hum Mol Genet. 2007. PMID: 17616514

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