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Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity.
Lambert PD, Anderson KD, Sleeman MW, Wong V, Tan J, Hijarunguru A, Corcoran TL, Murray JD, Thabet KE, Yancopoulos GD, Wiegand SJ. Lambert PD, et al. Among authors: wiegand sj. Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4652-7. doi: 10.1073/pnas.061034298. Epub 2001 Mar 20. Proc Natl Acad Sci U S A. 2001. PMID: 11259650 Free PMC article.
Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5.
Macdonald LE, Wortley KE, Gowen LC, Anderson KD, Murray JD, Poueymirou WT, Simmons MV, Barber D, Valenzuela DM, Economides AN, Wiegand SJ, Yancopoulos GD, Sleeman MW, Murphy AJ. Macdonald LE, et al. Among authors: wiegand sj. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2496-501. doi: 10.1073/pnas.0409849102. Epub 2005 Feb 7. Proc Natl Acad Sci U S A. 2005. PMID: 15699348 Free PMC article.
The ciliary neurotrophic factor and its receptor, CNTFR alpha.
Sleeman MW, Anderson KD, Lambert PD, Yancopoulos GD, Wiegand SJ. Sleeman MW, et al. Among authors: wiegand sj. Pharm Acta Helv. 2000 Mar;74(2-3):265-72. doi: 10.1016/s0031-6865(99)00050-3. Pharm Acta Helv. 2000. PMID: 10812968 Review.
149 results