Imai Y - Search Results

1

Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis.

Imai Y, Kurokawa M, Izutsu K, Hangaishi A, Maki K, Ogawa S, Chiba S, Mitani K, Hirai H. Imai Y, et al. Oncogene. 2001 Jan 4;20(1):88-96. doi: 10.1038/sj.onc.1204057. Oncogene. 2001. PMID: 11244507

2

The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.

Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H. Kurokawa M, et al. Among authors: imai y. Blood. 1998 Dec 1;92(11):4003-12. Blood. 1998. PMID: 9834202 Free article.

3

Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis.

Imai Y, Kurokawa M, Izutsu K, Hangaishi A, Takeuchi K, Maki K, Ogawa S, Chiba S, Mitani K, Hirai H. Imai Y, et al. Blood. 2000 Nov 1;96(9):3154-60. Blood. 2000. PMID: 11049997 Free article.

4

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling.

Izutsu K, Kurokawa M, Imai Y, Maki K, Mitani K, Hirai H. Izutsu K, et al. Among authors: imai y. Blood. 2001 May 1;97(9):2815-22. doi: 10.1182/blood.v97.9.2815. Blood. 2001. PMID: 11313276 Free article.

5

Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis.

Qiao Y, Ogawa S, Hangaishi A, Yuji K, Izutsu K, Kunisato A, Imai Y, Wang L, Hosoya N, Nannya Y, Sato Y, Maki K, Mitani K, Hirai H. Qiao Y, et al. Among authors: imai y. Leukemia. 2003 Jun;17(6):1112-20. doi: 10.1038/sj.leu.2402919. Leukemia. 2003. PMID: 12764377

6

The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability.

Tanaka T, Kurokawa M, Ueki K, Tanaka K, Imai Y, Mitani K, Okazaki K, Sagata N, Yazaki Y, Shibata Y, Kadowaki T, Hirai H. Tanaka T, et al. Among authors: imai y. Mol Cell Biol. 1996 Jul;16(7):3967-79. doi: 10.1128/MCB.16.7.3967. Mol Cell Biol. 1996. PMID: 8668214 Free PMC article.

7

The AML1/ETO(MTG8) and AML1/Evi-1 leukemia-associated chimeric oncoproteins accumulate PEBP2beta(CBFbeta) in the nucleus more efficiently than wild-type AML1.

Tanaka K, Tanaka T, Kurokawa M, Imai Y, Ogawa S, Mitani K, Yazaki Y, Hirai H. Tanaka K, et al. Among authors: imai y. Blood. 1998 Mar 1;91(5):1688-99. Blood. 1998. PMID: 9473235 Free article.

8

TLE, the human homolog of groucho, interacts with AML1 and acts as a repressor of AML1-induced transactivation.

Imai Y, Kurokawa M, Tanaka K, Friedman AD, Ogawa S, Mitani K, Yazaki Y, Hirai H. Imai Y, et al. Biochem Biophys Res Commun. 1998 Nov 27;252(3):582-9. doi: 10.1006/bbrc.1998.9705. Biochem Biophys Res Commun. 1998. PMID: 9837750 Free article.

9

Identification of Ki23819, a highly potent inhibitor of kinase activity of mutant FLT3 receptor tyrosine kinase.

Komeno Y, Kurokawa M, Imai Y, Takeshita M, Matsumura T, Kubo K, Yoshino T, Nishiyama U, Kuwaki T, Kubo K, Osawa T, Ogawa S, Chiba S, Miwa A, Hirai H. Komeno Y, et al. Among authors: imai y. Leukemia. 2005 Jun;19(6):930-5. doi: 10.1038/sj.leu.2403736. Leukemia. 2005. PMID: 15815726

10

Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.

Shimabe M, Goyama S, Watanabe-Okochi N, Yoshimi A, Ichikawa M, Imai Y, Kurokawa M. Shimabe M, et al. Among authors: imai y. Oncogene. 2009 Dec 10;28(49):4364-74. doi: 10.1038/onc.2009.288. Oncogene. 2009. PMID: 19767769

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