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Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling.
Young PW, Cawthorne MA, Coyle PJ, Holder JC, Holman GD, Kozka IJ, Kirkham DM, Lister CA, Smith SA. Young PW, et al. Among authors: smith sa. Diabetes. 1995 Sep;44(9):1087-92. doi: 10.2337/diab.44.9.1087. Diabetes. 1995. PMID: 7657033
Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter.
Pearce NJ, Arch JR, Clapham JC, Coghlan MP, Corcoran SL, Lister CA, Llano A, Moore GB, Murphy GJ, Smith SA, Taylor CM, Yates JW, Morrison AD, Harper AJ, Roxbee-Cox L, Abuin A, Wargent E, Holder JC. Pearce NJ, et al. Among authors: smith sa. Metabolism. 2004 Oct;53(10):1322-30. doi: 10.1016/j.metabol.2004.05.008. Metabolism. 2004. PMID: 15375789
Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids.
Haigh D, Allen G, Birrell HC, Buckle DR, Cantello BC, Eggleston DS, Haltiwanger RC, Holder JC, Lister CA, Pinto IL, Rami HK, Sime JT, Smith SA, Sweeney JD. Haigh D, et al. Among authors: smith sa. Bioorg Med Chem. 1999 May;7(5):821-30. doi: 10.1016/s0968-0896(99)00034-6. Bioorg Med Chem. 1999. PMID: 10400335
Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.
Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, Hockings PD, Reid DG, Squires SM, Hatcher J, Trail B, Latcham J, Rastan S, Harper AJ, Cadenas S, Buckingham JA, Brand MD, Abuin A. Clapham JC, et al. Among authors: smith sa. Nature. 2000 Jul 27;406(6794):415-8. doi: 10.1038/35019082. Nature. 2000. PMID: 10935638
1,631 results