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Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity.
Serradji N, Martin M, Bensaid O, Cisternino S, Rousselle C, Dereuddre-Bosquet N, Huet J, Redeuilh C, Lamouri A, Dong CZ, Clayette P, Scherrmann JM, Dormont D, Heymans F. Serradji N, et al. Among authors: heymans f. J Med Chem. 2004 Dec 2;47(25):6410-9. doi: 10.1021/jm040860g. J Med Chem. 2004. PMID: 15566310
Inhibition of secretory phospholipase A2. 2-Synthesis and structure-activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme.
Dong CZ, Ahamada-Himidi A, Plocki S, Aoun D, Touaibia M, Meddad-Bel Habich N, Huet J, Redeuilh C, Ombetta JE, Godfroid JJ, Massicot F, Heymans F. Dong CZ, et al. Among authors: heymans f. Bioorg Med Chem. 2005 Mar 15;13(6):1989-2007. doi: 10.1016/j.bmc.2005.01.016. Bioorg Med Chem. 2005. PMID: 15727853
Inhibition of secretory phospholipase A2. 1-design, synthesis and structure-activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLA2s.
Assogba L, Ahamada-Himidi A, Habich NM, Aoun D, Boukli L, Massicot F, Mounier CM, Huet J, Lamouri A, Ombetta JE, Godfroid JJ, Dong CZ, Heymans F. Assogba L, et al. Among authors: heymans f. Eur J Med Chem. 2005 Sep;40(9):850-61. doi: 10.1016/j.ejmech.2005.03.027. Eur J Med Chem. 2005. PMID: 16084626
Structure-activity relationships in platelet-activating factor. Part 13: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity.
Serradji N, Bensaid O, Martin M, Sallem W, Dereuddre-Bosquet N, Benmehdi H, Redeuilh C, Lamouri A, Dive G, Clayette P, Heymans F. Serradji N, et al. Among authors: heymans f. Bioorg Med Chem. 2006 Dec 1;14(23):8109-25. doi: 10.1016/j.bmc.2006.07.031. Epub 2006 Aug 8. Bioorg Med Chem. 2006. PMID: 16893650 Free article.
Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.
Meddad-Belhabich N, Aoun D, Djimdé A, Redeuilh C, Dive G, Massicot F, Chau F, Heymans F, Lamouri A. Meddad-Belhabich N, et al. Among authors: heymans f. Bioorg Med Chem. 2010 May 15;18(10):3588-600. doi: 10.1016/j.bmc.2010.03.049. Epub 2010 Mar 27. Bioorg Med Chem. 2010. PMID: 20417107 Free article.
63 results