Wang CC - Search Results

1

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).

Shi W, Munagala NR, Wang CC, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. Shi W, et al. Among authors: wang cc. Biochemistry. 2000 Jun 13;39(23):6781-90. doi: 10.1021/bi000128t. Biochemistry. 2000. PMID: 10841757

2

Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.

Munagala NR, Chin MS, Wang CC. Munagala NR, et al. Among authors: wang cc. Biochemistry. 1998 Mar 24;37(12):4045-51. doi: 10.1021/bi972515h. Biochemistry. 1998. PMID: 9521725

3

Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan.

Somoza JR, Skillman AG Jr, Munagala NR, Oshiro CM, Knegtel RM, Mpoke S, Fletterick RJ, Kuntz ID, Wang CC. Somoza JR, et al. Among authors: wang cc. Biochemistry. 1998 Apr 21;37(16):5344-8. doi: 10.1021/bi973095z. Biochemistry. 1998. PMID: 9548915

4

Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.

Munagala NR, Wang CC. Munagala NR, et al. Among authors: wang cc. Biochemistry. 1998 Nov 24;37(47):16612-9. doi: 10.1021/bi9818974. Biochemistry. 1998. PMID: 9843428

5

Point mutations in the guanine phosphoribosyltransferase from Giardia lamblia modulate pyrophosphate binding and enzyme catalysis.

Page JP, Munagala NR, Wang CC. Page JP, et al. Among authors: wang cc. Eur J Biochem. 1999 Feb;259(3):565-71. doi: 10.1046/j.1432-1327.1999.00020.x. Eur J Biochem. 1999. PMID: 10092838 Free article.

6

Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment.

Pitera JW, Munagala NR, Wang CC, Kollman PA. Pitera JW, et al. Among authors: wang cc. Biochemistry. 1999 Aug 10;38(32):10298-306. doi: 10.1021/bi990250w. Biochemistry. 1999. PMID: 10441123

7

Rational design of selective submicromolar inhibitors of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase.

Aronov AM, Munagala NR, Ortiz De Montellano PR, Kuntz ID, Wang CC. Aronov AM, et al. Among authors: wang cc. Biochemistry. 2000 Apr 25;39(16):4684-91. doi: 10.1021/bi992555g. Biochemistry. 2000. PMID: 10769124

8

Converting the guanine phosphoribosyltransferase from Giardia lamblia to a hypoxanthine-guanine phosphoribosyltransferase.

Munagala N, Sarver AE, Wang CC. Munagala N, et al. Among authors: wang cc. J Biol Chem. 2000 Nov 24;275(47):37072-7. doi: 10.1074/jbc.M007239200. J Biol Chem. 2000. PMID: 10976110 Free article.

9

Role of the flexible loop of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus in enzyme catalysis.

Munagala N, Basus VJ, Wang CC. Munagala N, et al. Among authors: wang cc. Biochemistry. 2001 Apr 10;40(14):4303-11. doi: 10.1021/bi0026932. Biochemistry. 2001. PMID: 11284686

10

Virtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase.

Aronov AM, Munagala NR, Kuntz ID, Wang CC. Aronov AM, et al. Among authors: wang cc. Antimicrob Agents Chemother. 2001 Sep;45(9):2571-6. doi: 10.1128/AAC.45.9.2571-2576.2001. Antimicrob Agents Chemother. 2001. PMID: 11502531 Free PMC article.

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