Hedstrom R - Search Results

1

Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus.

Sedegah M, Weiss W, Sacci JB Jr, Charoenvit Y, Hedstrom R, Gowda K, Majam VF, Tine J, Kumar S, Hobart P, Hoffman SL. Sedegah M, et al. Among authors: hedstrom r. J Immunol. 2000 Jun 1;164(11):5905-12. doi: 10.4049/jimmunol.164.11.5905. J Immunol. 2000. PMID: 10820272

2

A DNA vaccine encoding the 42 kDa C-terminus of merozoite surface protein 1 of Plasmodium falciparum induces antibody, interferon-gamma and cytotoxic T cell responses in rhesus monkeys: immuno-stimulatory effects of granulocyte macrophage-colony stimulating factor.

Kumar S, Villinger F, Oakley M, Aguiar JC, Jones TR, Hedstrom RC, Gowda K, Chute J, Stowers A, Kaslow DC, Thomas EK, Tine J, Klinman D, Hoffman SL, Weiss WW. Kumar S, et al. Among authors: hedstrom rc. Immunol Lett. 2002 Apr 1;81(1):13-24. doi: 10.1016/s0165-2478(01)00316-9. Immunol Lett. 2002. PMID: 11841841

3

Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA.

Richie TL, Charoenvit Y, Wang R, Epstein JE, Hedstrom RC, Kumar S, Luke TC, Freilich DA, Aguiar JC, Sacci JB Jr, Sedegah M, Nosek RA Jr, De La Vega P, Berzins MP, Majam VF, Abot EN, Ganeshan H, Richie NO, Banania JG, Baraceros MF, Geter TG, Mere R, Bebris L, Limbach K, Hickey BW, Lanar DE, Ng J, Shi M, Hobart PM, Norman JA, Soisson LA, Hollingdale MR, Rogers WO, Doolan DL, Hoffman SL. Richie TL, et al. Among authors: hedstrom rc. Hum Vaccin Immunother. 2012 Nov 1;8(11):1564-84. doi: 10.4161/hv.22129. Epub 2012 Nov 1. Hum Vaccin Immunother. 2012. PMID: 23151451 Free PMC article. Clinical Trial.

4

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

Sedegah M, Hedstrom R, Hobart P, Hoffman SL. Sedegah M, et al. Among authors: hedstrom r. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9866-70. doi: 10.1073/pnas.91.21.9866. Proc Natl Acad Sci U S A. 1994. PMID: 7937907 Free PMC article.

5

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine.

Sedegah M, Jones TR, Kaur M, Hedstrom R, Hobart P, Tine JA, Hoffman SL. Sedegah M, et al. Among authors: hedstrom r. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7648-53. doi: 10.1073/pnas.95.13.7648. Proc Natl Acad Sci U S A. 1998. PMID: 9636204 Free PMC article.

6

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.

Sedegah M, Charoenvit Y, Aguiar J, Sacci J, Hedstrom R, Kumar S, Belmonte A, Lanar DE, Jones TR, Abot E, Druilhe P, Corradin G, Epstein JE, Richie TL, Carucci DJ, Hoffman SL. Sedegah M, et al. Among authors: hedstrom r. Genes Immun. 2004 Nov;5(7):553-61. doi: 10.1038/sj.gene.6364125. Genes Immun. 2004. PMID: 15318164

7

Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine.

Hoffman SL, Sedegah M, Hedstrom RC. Hoffman SL, et al. Among authors: hedstrom rc. Vaccine. 1994 Dec;12(16):1529-33. doi: 10.1016/0264-410x(94)90078-7. Vaccine. 1994. PMID: 7879419

8

Prospects and strategies for development of DNA vaccines against malaria.

Hedstrom RC, Sedegah M, Hoffman SL. Hedstrom RC, et al. Res Immunol. 1994 Jul-Aug;145(6):476-83. doi: 10.1016/s0923-2494(94)80179-7. Res Immunol. 1994. PMID: 7899711 Review. No abstract available.

9

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.

Doolan DL, Sedegah M, Hedstrom RC, Hobart P, Charoenvit Y, Hoffman SL. Doolan DL, et al. Among authors: hedstrom rc. J Exp Med. 1996 Apr 1;183(4):1739-46. doi: 10.1084/jem.183.4.1739. J Exp Med. 1996. PMID: 8666931 Free PMC article.

10

Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use.

Hoffman SL, Doolan DL, Sedegah M, Aguiar JC, Wang R, Malik A, Gramzinski RA, Weiss WR, Hobart P, Norman JA, Margalith M, Hedstrom RC. Hoffman SL, et al. Among authors: hedstrom rc. Vaccine. 1997 Jun;15(8):842-5. doi: 10.1016/s0264-410x(96)00273-3. Vaccine. 1997. PMID: 9234529

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