Normandin D - Search Results

1

N-3-substituted imidazoquinazolinones: potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction.

Rotella DP, Sun Z, Zhu Y, Krupinski J, Pongrac R, Seliger L, Normandin D, Macor JE. Rotella DP, et al. Among authors: normandin d. J Med Chem. 2000 Apr 6;43(7):1257-63. doi: 10.1021/jm000081+. J Med Chem. 2000. PMID: 10753463

2

Substituted pyrazolopyridopyridazines as orally bioavailable potent and selective PDE5 inhibitors: potential agents for treatment of erectile dysfunction.

Yu G, Mason H, Wu X, Wang J, Chong S, Beyer B, Henwood A, Pongrac R, Seliger L, He B, Normandin D, Ferrer P, Zhang R, Adam L, Humphrey WG, Krupinski J, Macor JE. Yu G, et al. Among authors: normandin d. J Med Chem. 2003 Feb 13;46(4):457-60. doi: 10.1021/jm0256068. J Med Chem. 2003. PMID: 12570368

3

Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction.

Bi Y, Stoy P, Adam L, He B, Krupinski J, Normandin D, Pongrac R, Seliger L, Watson A, Macor JE. Bi Y, et al. Among authors: normandin d. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1577-80. doi: 10.1016/j.bmcl.2003.12.090. Bioorg Med Chem Lett. 2004. PMID: 15006407

4

Optimization of substituted N-3-benzylimidazoquinazolinone sulfonamides as potent and selective PDE5 inhibitors.

Rotella DP, Sun Z, Zhu Y, Krupinski J, Pongrac R, Seliger L, Normandin D, Macor JE. Rotella DP, et al. Among authors: normandin d. J Med Chem. 2000 Dec 28;43(26):5037-43. doi: 10.1021/jm000336j. J Med Chem. 2000. PMID: 11150175

5

Substituted pyrazolopyridines as potent and selective PDE5 inhibitors: potential agents for treatment of erectile dysfunction.

Yu G, Mason HJ, Wu X, Wang J, Chong S, Dorough G, Henwood A, Pongrac R, Seliger L, He B, Normandin D, Adam L, Krupinski J, Macor JE. Yu G, et al. Among authors: normandin d. J Med Chem. 2001 Mar 29;44(7):1025-7. doi: 10.1021/jm0155042. J Med Chem. 2001. PMID: 11297448 No abstract available.

6

The discovery of novel, potent and selective PDE5 inhibitors.

Bi Y, Stoy P, Adam L, He B, Krupinski J, Normandin D, Pongrac R, Seliger L, Watson A, Macor JE. Bi Y, et al. Among authors: normandin d. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2461-4. doi: 10.1016/s0960-894x(01)00466-8. Bioorg Med Chem Lett. 2001. PMID: 11549447

7

Cardioselective antiischemic ATP-sensitive potassium channel openers. 4. Structure-activity studies on benzopyranylcyanoguanidines: replacement of the benzopyran portion.

Atwal KS, Ferrara FN, Ding CZ, Grover GJ, Sleph PG, Dzwonczyk S, Baird AJ, Normandin DE. Atwal KS, et al. Among authors: normandin de. J Med Chem. 1996 Jan 5;39(1):304-13. doi: 10.1021/jm950646f. J Med Chem. 1996. PMID: 8568821

8

Cardioselective antiischemic ATP-sensitive potassium channel (KATP) openers. 5. Identification of 4-(N-aryl)-substituted benzopyran derivatives with high selectivity.

Rovnyak GC, Ahmed SZ, Ding CZ, Dzwonczyk S, Ferrara FN, Humphreys WG, Grover GJ, Santafianos D, Atwal KS, Baird AJ, McLaughlin LG, Normandin DE, Sleph PG, Traeger SC. Rovnyak GC, et al. Among authors: normandin de. J Med Chem. 1997 Jan 3;40(1):24-34. doi: 10.1021/jm9605905. J Med Chem. 1997. PMID: 9016325

9

Cardioselective anti-ischemic ATP-sensitive potassium channel openers. 3. Structure-activity studies on benzopyranyl cyanoguanidines: modification of the cyanoguanidine portion.

Atwal KS, Grover GJ, Ahmed SZ, Sleph PG, Dzwonczyk S, Baird AJ, Normandin DE. Atwal KS, et al. Among authors: normandin de. J Med Chem. 1995 Aug 18;38(17):3236-45. doi: 10.1021/jm00017a007. J Med Chem. 1995. PMID: 7650676

10

Cardioselective antiischemic ATP-sensitive potassium channel openers. 2. Structure-activity studies on benzopyranylcyanoguanidines: modification of the benzopyran ring.

Atwal KS, Grover GJ, Ferrara FN, Ahmed SZ, Sleph PG, Dzwonczyk S, Normandin DE. Atwal KS, et al. Among authors: normandin de. J Med Chem. 1995 May 26;38(11):1966-73. doi: 10.1021/jm00011a016. J Med Chem. 1995. PMID: 7783128

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