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Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer.
Giacchetti S, Perpoint B, Zidani R, Le Bail N, Faggiuolo R, Focan C, Chollet P, Llory JF, Letourneau Y, Coudert B, Bertheaut-Cvitkovic F, Larregain-Fournier D, Le Rol A, Walter S, Adam R, Misset JL, Lévi F. Giacchetti S, et al. Among authors: adam r. J Clin Oncol. 2000 Jan;18(1):136-47. doi: 10.1200/JCO.2000.18.1.136. J Clin Oncol. 2000. PMID: 10623704 Clinical Trial.
A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer.
Lévi F, Misset JL, Brienza S, Adam R, Metzger G, Itzakhi M, Caussanel JP, Kunstlinger F, Lecouturier S, Descorps-Declère A, et al. Lévi F, et al. Among authors: adam r. Cancer. 1992 Feb 15;69(4):893-900. doi: 10.1002/1097-0142(19920215)69:4<893::aid-cncr2820690410>3.0.co;2-x. Cancer. 1992. PMID: 1735081 Clinical Trial.
Implications of chronobiology for 5-fluorouracil (5-FU) efficacy.
Lévi F, Brienza S, Metzer G, Deprés-Brummer P, Bertheault-Cvitkovic F, Zidani R, Adam R, Misset JL. Lévi F, et al. Among authors: adam r. Adv Exp Med Biol. 1993;339:169-83. doi: 10.1007/978-1-4615-2488-5_18. Adv Exp Med Biol. 1993. PMID: 8178715 Review. No abstract available.
1,462 results