Hardwick JS - Search Results

1

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.

Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.

2

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein.

Peterson RT, Desai BN, Hardwick JS, Schreiber SL. Peterson RT, et al. Among authors: hardwick js. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4438-42. doi: 10.1073/pnas.96.8.4438. Proc Natl Acad Sci U S A. 1999. PMID: 10200280 Free PMC article.

3

Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers.

Saadi A, Shannon NB, Lao-Sirieix P, O'Donovan M, Walker E, Clemons NJ, Hardwick JS, Zhang C, Das M, Save V, Novelli M, Balkwill F, Fitzgerald RC. Saadi A, et al. Among authors: hardwick js. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):2177-82. doi: 10.1073/pnas.0909797107. Epub 2010 Jan 13. Proc Natl Acad Sci U S A. 2010. PMID: 20080664 Free PMC article.

4

Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.

Hardwick JS, Sefton BM. Hardwick JS, et al. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4527-31. doi: 10.1073/pnas.92.10.4527. Proc Natl Acad Sci U S A. 1995. PMID: 7538674 Free PMC article.

5

A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia.

Peters CJ, Rees JR, Hardwick RH, Hardwick JS, Vowler SL, Ong CA, Zhang C, Save V, O'Donovan M, Rassl D, Alderson D, Caldas C, Fitzgerald RC; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group. Peters CJ, et al. Among authors: hardwick rh, hardwick js. Gastroenterology. 2010 Dec;139(6):1995-2004.e15. doi: 10.1053/j.gastro.2010.05.080. Epub 2010 Jun 2. Gastroenterology. 2010. PMID: 20621683

6

Stimulation of phosphorylation of Tyr394 by hydrogen peroxide reactivates biologically inactive, non-membrane-bound forms of Lck.

Yurchak LK, Hardwick JS, Amrein K, Pierno K, Sefton BM. Yurchak LK, et al. Among authors: hardwick js. J Biol Chem. 1996 May 24;271(21):12549-54. doi: 10.1074/jbc.271.21.12549. J Biol Chem. 1996. PMID: 8647864 Free article.

7

The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505.

Hardwick JS, Sefton BM. Hardwick JS, et al. J Biol Chem. 1997 Oct 10;272(41):25429-32. doi: 10.1074/jbc.272.41.25429. J Biol Chem. 1997. PMID: 9325251 Free article.

8

Activation of the lck tyrosine-protein kinase by the binding of the tip protein of herpesvirus saimiri in the absence of regulatory tyrosine phosphorylation.

Hartley DA, Hurley TR, Hardwick JS, Lund TC, Medveczky PG, Sefton BM. Hartley DA, et al. Among authors: hardwick js. J Biol Chem. 1999 Jul 16;274(29):20056-9. doi: 10.1074/jbc.274.29.20056. J Biol Chem. 1999. PMID: 10400611 Free article.

9

Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling.

Hardwick JS, Yang Y, Zhang C, Shi B, McFall R, Koury EJ, Hill SL, Dai H, Wasserman R, Phillips RL, Weinstein EJ, Kohl NE, Severino ME, Lamb JR, Sepp-Lorenzino L. Hardwick JS, et al. Mol Cancer Ther. 2005 Mar;4(3):413-25. doi: 10.1158/1535-7163.MCT-04-0209. Mol Cancer Ther. 2005. PMID: 15767550

10

Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer.

Cao J, Zhu Z, Wang H, Nichols TC, Lui GYL, Deng S, Rejto PA, VanArsdale T, Hardwick JS, Weinrich SL, Wei P. Cao J, et al. Among authors: hardwick js. Oncogene. 2019 May;38(21):4125-4141. doi: 10.1038/s41388-019-0708-7. Epub 2019 Jan 30. Oncogene. 2019. PMID: 30700828

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