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Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin.
Cruz MC, Del Poeta M, Wang P, Wenger R, Zenke G, Quesniaux VF, Movva NR, Perfect JR, Cardenas ME, Heitman J. Cruz MC, et al. Among authors: perfect jr. Antimicrob Agents Chemother. 2000 Jan;44(1):143-9. doi: 10.1128/AAC.44.1.143-149.2000. Antimicrob Agents Chemother. 2000. PMID: 10602736 Free PMC article.
Infection and cyclosporine.
Kim JH, Perfect JR. Kim JH, et al. Among authors: perfect jr. Rev Infect Dis. 1989 Sep-Oct;11(5):677-90. doi: 10.1093/clinids/11.5.677. Rev Infect Dis. 1989. PMID: 2682942 Review.
Uptake of itraconazole by alveolar macrophages.
Perfect JR, Savani DV, Durack DT. Perfect JR, et al. Antimicrob Agents Chemother. 1993 Apr;37(4):903-4. doi: 10.1128/AAC.37.4.903. Antimicrob Agents Chemother. 1993. PMID: 8388205 Free PMC article.
522 results