Pilger BD - Search Results

1

Substrate diversity of herpes simplex virus thymidine kinase. Impact Of the kinematics of the enzyme.

Pilger BD, Perozzo R, Alber F, Wurth C, Folkers G, Scapozza L. Pilger BD, et al. J Biol Chem. 1999 Nov 5;274(45):31967-73. doi: 10.1074/jbc.274.45.31967. J Biol Chem. 1999. PMID: 10542226 Free article.

2

Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine.

Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L. Prota A, et al. Biochemistry. 2000 Aug 8;39(31):9597-603. doi: 10.1021/bi000668q. Biochemistry. 2000. PMID: 10924157

3

Drug resistance of herpes simplex virus type 1--structural considerations at the molecular level of the thymidine kinase.

Kussmann-Gerber S, Kuonen O, Folkers G, Pilger BD, Scapozza L. Kussmann-Gerber S, et al. Among authors: pilger bd. Eur J Biochem. 1998 Jul 15;255(2):472-81. doi: 10.1046/j.1432-1327.1998.2550472.x. Eur J Biochem. 1998. PMID: 9716390 Free article.

4

Interaction of the recombinant herpes simplex virus type 1 thymidine kinase with thymidine and aciclovir: a kinetic study.

Kussmann-Gerber S, Wurth C, Scapozza L, Pilger BD, Pliska V, Folkers G. Kussmann-Gerber S, et al. Among authors: pilger bd. Nucleosides Nucleotides. 1999 Mar;18(3):311-30. doi: 10.1080/15257779908043078. Nucleosides Nucleotides. 1999. PMID: 10358938

5

Nucleoside binding site of herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography.

Vogt J, Perozzo R, Pautsch A, Prota A, Schelling P, Pilger B, Folkers G, Scapozza L, Schulz GE. Vogt J, et al. Proteins. 2000 Dec 1;41(4):545-53. doi: 10.1002/1097-0134(20001201)41:4<545::aid-prot110>3.0.co;2-8. Proteins. 2000. PMID: 11056041

6

Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication.

Pilger BD, Cui C, Coen DM. Pilger BD, et al. Chem Biol. 2004 May;11(5):647-54. doi: 10.1016/j.chembiol.2004.01.018. Chem Biol. 2004. PMID: 15157875

7

High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction.

Tintori C, Laurenzana I, Fallacara AL, Kessler U, Pilger B, Stergiou L, Botta M. Tintori C, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):280-2. doi: 10.1016/j.bmcl.2013.11.019. Epub 2013 Nov 21. Bioorg Med Chem Lett. 2014. PMID: 24314669

8

The fight against the influenza A virus H1N1: synthesis, molecular modeling, and biological evaluation of benzofurazan derivatives as viral RNA polymerase inhibitors.

Pagano M, Castagnolo D, Bernardini M, Fallacara AL, Laurenzana I, Deodato D, Kessler U, Pilger B, Stergiou L, Strunze S, Tintori C, Botta M. Pagano M, et al. ChemMedChem. 2014 Jan;9(1):129-50. doi: 10.1002/cmdc.201300378. Epub 2013 Nov 27. ChemMedChem. 2014. PMID: 24285596

9

Discovery and synthesis of novel benzofurazan derivatives as inhibitors of influenza A virus.

Kessler U, Castagnolo D, Pagano M, Deodato D, Bernardini M, Pilger B, Ranadheera C, Botta M. Kessler U, et al. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5575-7. doi: 10.1016/j.bmcl.2013.08.048. Epub 2013 Aug 17. Bioorg Med Chem Lett. 2013. PMID: 24012120

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