Stammers DK - Search Results

1

Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies.

Ren J, Esnouf RM, Hopkins AL, Stuart DI, Stammers DK. Ren J, et al. Among authors: stammers dk. J Med Chem. 1999 Sep 23;42(19):3845-51. doi: 10.1021/jm990275t. J Med Chem. 1999. PMID: 10508433

2

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Hopkins AL, et al. Among authors: stammers dk. J Med Chem. 2004 Nov 18;47(24):5912-22. doi: 10.1021/jm040071z. J Med Chem. 2004. PMID: 15537346

3

Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.

Freeman GA, Andrews Iii CW 3rd, Hopkins AL, Lowell GS, Schaller LT, Cowan JR, Gonzales SS, Koszalka GW, Hazen RJ, Boone LR, Ferris RG, Creech KL, Roberts GB, Short SA, Weaver K, Reynolds DJ, Milton J, Ren J, Stuart DI, Stammers DK, Chan JH. Freeman GA, et al. Among authors: stammers dk. J Med Chem. 2004 Nov 18;47(24):5923-36. doi: 10.1021/jm040072r. J Med Chem. 2004. PMID: 15537347

4

HIV reverse transcriptase structures: designing new inhibitors and understanding mechanisms of drug resistance.

Ren J, Stammers DK. Ren J, et al. Among authors: stammers dk. Trends Pharmacol Sci. 2005 Jan;26(1):4-7. doi: 10.1016/j.tips.2004.11.003. Trends Pharmacol Sci. 2005. PMID: 15629197 Review.

5

Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.

Ren J, Stammers DK. Ren J, et al. Among authors: stammers dk. Virus Res. 2008 Jun;134(1-2):157-70. doi: 10.1016/j.virusres.2007.12.018. Epub 2008 Mar 3. Virus Res. 2008. PMID: 18313784 Review.

6

Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors.

Ren J, Chamberlain PP, Stamp A, Short SA, Weaver KL, Romines KR, Hazen R, Freeman A, Ferris RG, Andrews CW, Boone L, Chan JH, Stammers DK. Ren J, et al. Among authors: stammers dk. J Med Chem. 2008 Aug 28;51(16):5000-8. doi: 10.1021/jm8004493. Epub 2008 Jul 30. J Med Chem. 2008. PMID: 18665583

7

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.

Esnouf R, Ren J, Ross C, Jones Y, Stammers D, Stuart D. Esnouf R, et al. Nat Struct Biol. 1995 Apr;2(4):303-8. doi: 10.1038/nsb0495-303. Nat Struct Biol. 1995. PMID: 7540935

8

The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.

Ren J, Esnouf R, Hopkins A, Ross C, Jones Y, Stammers D, Stuart D. Ren J, et al. Structure. 1995 Sep 15;3(9):915-26. doi: 10.1016/S0969-2126(01)00226-X. Structure. 1995. PMID: 8535785 Free article.

9

Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.

Esnouf RM, Ren J, Garman EF, Somers DO, Ross CK, Jones EY, Stammers DK, Stuart DI. Esnouf RM, et al. Among authors: stammers dk. Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):938-53. doi: 10.1107/s0907444998004284. Acta Crystallogr D Biol Crystallogr. 1998. PMID: 9757109

10

Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.

Ren J, Esnouf RM, Hopkins AL, Warren J, Balzarini J, Stuart DI, Stammers DK. Ren J, et al. Among authors: stammers dk. Biochemistry. 1998 Oct 13;37(41):14394-403. doi: 10.1021/bi981309m. Biochemistry. 1998. PMID: 9772165

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