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De novo amyloid proteins from designed combinatorial libraries.
West MW, Wang W, Patterson J, Mancias JD, Beasley JR, Hecht MH. West MW, et al. Among authors: hecht mh. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11211-6. doi: 10.1073/pnas.96.20.11211. Proc Natl Acad Sci U S A. 1999. PMID: 10500156 Free PMC article.
De novo design of beta-sheet proteins.
Hecht MH. Hecht MH. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8729-30. doi: 10.1073/pnas.91.19.8729. Proc Natl Acad Sci U S A. 1994. PMID: 8090714 Free PMC article. No abstract available.
Protein design: the choice of de novo sequences.
Beasley JR, Hecht MH. Beasley JR, et al. Among authors: hecht mh. J Biol Chem. 1997 Jan 24;272(4):2031-4. doi: 10.1074/jbc.272.4.2031. J Biol Chem. 1997. PMID: 9036150 Free article. Review. No abstract available.
Minimized protein structures: a little goes a long way.
Nedwidek MN, Hecht MH. Nedwidek MN, et al. Among authors: hecht mh. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10010-1. doi: 10.1073/pnas.94.19.10010. Proc Natl Acad Sci U S A. 1997. PMID: 9294152 Free PMC article. Review. No abstract available.
De novo heme proteins from designed combinatorial libraries.
Rojas NR, Kamtekar S, Simons CT, McLean JE, Vogel KM, Spiro TG, Farid RS, Hecht MH. Rojas NR, et al. Among authors: hecht mh. Protein Sci. 1997 Dec;6(12):2512-24. doi: 10.1002/pro.5560061204. Protein Sci. 1997. PMID: 9416601 Free PMC article.
The design of these sequences was based on a "binary code" strategy, in which the patterning of polar and nonpolar amino acids is specified explicitly, but the exact identities of the side chains is varied extensively (Kamtekar S, Schiffer JM, Xiong H, Babik JM, Hecht M …
The design of these sequences was based on a "binary code" strategy, in which the patterning of polar and nonpolar amino acids is specified …
107 results