Ilyas M - Search Results

1

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.

Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, Roylance R, Gorman P, Sheer D, Neale K, Phillips R, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Among authors: ilyas m. Nat Med. 1999 Sep;5(9):1071-5. doi: 10.1038/12511. Nat Med. 1999. PMID: 10470088

2

Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.

Homfray TF, Cottrell SE, Ilyas M, Rowan A, Talbot IC, Bodmer WF, Tomlinson IP. Homfray TF, et al. Among authors: ilyas m. Hum Mutat. 1998;11(2):114-20. doi: 10.1002/(SICI)1098-1004(1998)11:2<114::AID-HUMU3>3.0.CO;2-J. Hum Mutat. 1998. PMID: 9482574

3

APC mutations are sufficient for the growth of early colorectal adenomas.

Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I. Lamlum H, et al. Among authors: ilyas m. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2225-8. doi: 10.1073/pnas.040564697. Proc Natl Acad Sci U S A. 2000. PMID: 10681434 Free PMC article.

4

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits".

Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. Rowan AJ, et al. Among authors: ilyas m. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3352-7. doi: 10.1073/pnas.97.7.3352. Proc Natl Acad Sci U S A. 2000. PMID: 10737795 Free PMC article.

5

The interactions of APC, E-cadherin and beta-catenin in tumour development and progression.

Ilyas M, Tomlinson IP. Ilyas M, et al. J Pathol. 1997 Jun;182(2):128-37. doi: 10.1002/(SICI)1096-9896(199706)182:2<128::AID-PATH839>3.0.CO;2-Q. J Pathol. 1997. PMID: 9274521 Review.

6

Beta-catenin mutations in cell lines established from human colorectal cancers.

Ilyas M, Tomlinson IP, Rowan A, Pignatelli M, Bodmer WF. Ilyas M, et al. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10330-4. doi: 10.1073/pnas.94.19.10330. Proc Natl Acad Sci U S A. 1997. PMID: 9294210 Free PMC article.

7

A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.

Tomlinson I, Ilyas M, Johnson V, Davies A, Clark G, Talbot I, Bodmer W. Tomlinson I, et al. Among authors: ilyas m. J Pathol. 1998 Feb;184(2):148-52. doi: 10.1002/(SICI)1096-9896(199802)184:2<148::AID-PATH986>3.0.CO;2-M. J Pathol. 1998. PMID: 9602705

8

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.

Frayling IM, Beck NE, Ilyas M, Dove-Edwin I, Goodman P, Pack K, Bell JA, Williams CB, Hodgson SV, Thomas HJ, Talbot IC, Bodmer WF, Tomlinson IP. Frayling IM, et al. Among authors: ilyas m. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10722-7. doi: 10.1073/pnas.95.18.10722. Proc Natl Acad Sci U S A. 1998. PMID: 9724771 Free PMC article.

9

Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression.

Ilyas M, Efstathiou JA, Straub J, Kim HC, Bodmer WF. Ilyas M, et al. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3087-91. doi: 10.1073/pnas.96.6.3087. Proc Natl Acad Sci U S A. 1999. PMID: 10077641 Free PMC article.

10

Genetic pathways in colorectal and other cancers.

Ilyas M, Straub J, Tomlinson IP, Bodmer WF. Ilyas M, et al. Eur J Cancer. 1999 Mar;35(3):335-51. doi: 10.1016/s0959-8049(98)00431-6. Eur J Cancer. 1999. PMID: 10448282 Review.

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