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Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.
Ames RS, Lee D, Foley JJ, Jurewicz AJ, Tornetta MA, Bautsch W, Settmacher B, Klos A, Erhard KF, Cousins RD, Sulpizio AC, Hieble JP, McCafferty G, Ward KW, Adams JL, Bondinell WE, Underwood DC, Osborn RR, Badger AM, Sarau HM. Ames RS, et al. Among authors: settmacher b. J Immunol. 2001 May 15;166(10):6341-8. doi: 10.4049/jimmunol.166.10.6341. J Immunol. 2001. PMID: 11342658