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Cytosine deaminase/5-fluorocytosine gene therapy can induce efficient anti-tumor effects and protective immunity in immunocompetent mice but not in athymic nude mice.
Kuriyama S, Kikukawa M, Masui K, Okuda H, Nakatani T, Sakamoto T, Yoshiji H, Fukui H, Ikenaka K, Mullen CA, Tsujii T. Kuriyama S, et al. Among authors: kikukawa m. Int J Cancer. 1999 May 17;81(4):592-7. doi: 10.1002/(sici)1097-0215(19990517)81:4<592::aid-ijc15>3.0.co;2-i. Int J Cancer. 1999. PMID: 10225450
Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo.
Kuriyama S, Kikukawa M, Masui K, Okuda H, Nakatani T, Akahane T, Mitoro A, Tominaga K, Tsujinoue H, Yoshiji H, Okamoto S, Fukui H, Ikenaka K. Kuriyama S, et al. Among authors: kikukawa m. Int J Cancer. 1999 Oct 29;83(3):374-80. doi: 10.1002/(sici)1097-0215(19991029)83:3<374::aid-ijc13>3.0.co;2-#. Int J Cancer. 1999. PMID: 10495430
96 results