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Page 1
Potential role of muscarinic receptors in schizophrenia.
Bymaster FP, Shannon HE, Rasmussen K, DeLapp NW, Ward JS, Calligaro DO, Mitch CH, Whitesitt C, Ludvigsen TS, Sheardown M, Swedberg M, Rasmussen T, Olesen PH, Jeppesen L, Sauerberg P, Fink-Jensen A. Bymaster FP, et al. Among authors: whitesitt c. Life Sci. 1999;64(6-7):527-34. doi: 10.1016/s0024-3205(98)00597-9. Life Sci. 1999. PMID: 10069519
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects.
Bymaster FP, Carter PA, Peters SC, Zhang W, Ward JS, Mitch CH, Calligaro DO, Whitesitt CA, DeLapp N, Shannon HE, Rimvall K, Jeppesen L, Sheardown MJ, Fink-Jensen A, Sauerberg P. Bymaster FP, et al. Among authors: whitesitt ca. Brain Res. 1998 Jun 8;795(1-2):179-90. doi: 10.1016/s0006-8993(98)00267-4. Brain Res. 1998. PMID: 9622623
1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists.
Ward JS, Merritt L, Calligaro DO, Bymaster FP, Shannon HE, Mitch CH, Whitesitt C, Brunsting D, Sheardown MJ, Olesen PH, Swedberg MD, Jeppesen L, Sauerberg P. Ward JS, et al. Among authors: whitesitt c. J Med Chem. 1998 Jan 29;41(3):379-92. doi: 10.1021/jm970125n. J Med Chem. 1998. PMID: 9464368
Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation.
Sauerberg P, Jeppesen L, Olesen PH, Sheardown MJ, Fink-Jensen A, Rasmussen T, Rimvall K, Shannon HE, Bymaster FP, DeLapp NW, Calligaro DO, Ward JS, Whitesitt CA, Thomsen C. Sauerberg P, et al. Among authors: whitesitt ca. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2897-902. doi: 10.1016/s0960-894x(98)00509-5. Bioorg Med Chem Lett. 1998. PMID: 9873644
1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0(2,6)]heptanes as new potent muscarinic M1 agonists: structure-activity relationship for 3-aryl-2-propyn-1-yloxy and 3-aryl-2-propyn-1-ylthio derivatives.
Jeppesen L, Olesen PH, Hansen L, Sheardown MJ, Thomsen C, Rasmussen T, Jensen AF, Christensen MS, Rimvall K, Ward JS, Whitesitt C, Calligaro DO, Bymaster FP, Delapp NW, Felder CC, Shannon HE, Sauerberg P. Jeppesen L, et al. Among authors: whitesitt c. J Med Chem. 1999 Jun 3;42(11):1999-2006. doi: 10.1021/jm9910019. J Med Chem. 1999. PMID: 10354408
Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice.
Rasmussen T, Sauerberg P, Nielsen EB, Swedberg MD, Thomsen C, Sheardown MJ, Jeppesen L, Calligaro DO, DeLapp NW, Whitesitt C, Ward JS, Shannon HE, Bymaster FP, Fink-Jensen A. Rasmussen T, et al. Among authors: whitesitt c. Eur J Pharmacol. 2000 Aug 25;402(3):241-6. doi: 10.1016/s0014-2999(00)00442-8. Eur J Pharmacol. 2000. PMID: 10958890
The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance.
Rasmussen T, Fink-Jensen A, Sauerberg P, Swedberg MD, Thomsen C, Sheardown MJ, Jeppesen L, Calligaro DO, DeLapp NW, Whitesitt C, Ward JS, Shannon HE, Bymaster FP. Rasmussen T, et al. Among authors: whitesitt c. Schizophr Res. 2001 Apr 15;49(1-2):193-201. doi: 10.1016/s0920-9964(00)00129-8. Schizophr Res. 2001. PMID: 11343877
Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.
DeLapp N, Wu S, Belagaje R, Johnstone E, Little S, Shannon H, Bymaster F, Calligaro D, Mitch C, Whitesitt C, Ward J, Sheardown M, Fink-Jensen A, Jeppesen L, Thomsen C, Sauerberg P. DeLapp N, et al. Among authors: whitesitt c. Biochem Biophys Res Commun. 1998 Mar 6;244(1):156-60. doi: 10.1006/bbrc.1998.8235. Biochem Biophys Res Commun. 1998. PMID: 9514902
20 results