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Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells.
Wei SJ, Chang RL, Bhachech N, Cui XX, Merkler KA, Wong CQ, Hennig E, Yagi H, Jerina DM, Conney AH. Wei SJ, et al. Among authors: merkler ka. Cancer Res. 1993 Jul 15;53(14):3294-301. Cancer Res. 1993. PMID: 8324741
Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).
Merkler DJ, Asser AS, Baumgart LE, Carballo N, Carpenter SE, Chew GH, Cosner CC, Dusi J, Galloway LC, Lowe AB, Lowe EW Jr, King L 3rd, Kendig RD, Kline PC, Malka R, Merkler KA, McIntyre NR, Romero M, Wilcox BJ, Owen TC. Merkler DJ, et al. Among authors: merkler ka. Bioorg Med Chem. 2008 Dec 1;16(23):10061-74. doi: 10.1016/j.bmc.2008.10.013. Epub 2008 Oct 11. Bioorg Med Chem. 2008. PMID: 18952446 Free PMC article.
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