Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis

Am J Gastroenterol. 1998 Oct;93(10):1985-6. doi: 10.1111/j.1572-0241.1998.00561.x.

Abstract

Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver frequently associated with extrahepatic autoimmune phenomena. Specific antibodies against platelet glycoproteins may play an important role in the pathogenesis of thrombocytopenia associated with PBC. This is the first report of life-threatening idiopathic thrombocytopenic purpura successfully treated with steroids in a 62-yr-old woman 2 yr after liver transplantation for PBC.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Liver Cirrhosis, Biliary / surgery*
  • Liver Transplantation*
  • Middle Aged
  • Postoperative Complications / drug therapy*
  • Postoperative Complications / immunology
  • Prednisolone / therapeutic use*
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Purpura, Thrombocytopenic, Idiopathic / immunology

Substances

  • Glucocorticoids
  • Prednisolone