Trisomy 3q11-q29 is recurrently observed in B-cell non-Hodgkin's lymphomas associated with cold agglutinin syndrome

L Michaux; J Dierlamm; L Wlodarska; A Criel; A Louwagie; A Ferrant; A Hagemeijer; H Van den Berghe

doi:10.1007/s002770050389

Trisomy 3q11-q29 is recurrently observed in B-cell non-Hodgkin's lymphomas associated with cold agglutinin syndrome

Ann Hematol. 1998 May;76(5):201-4. doi: 10.1007/s002770050389.

Authors

L Michaux¹, J Dierlamm, L Wlodarska, A Criel, A Louwagie, A Ferrant, A Hagemeijer, H Van den Berghe

Affiliation

¹ Center for Human Genetics, University of Leuven, Belgium.

PMID: 9671133
DOI: 10.1007/s002770050389

Abstract

Three cases of low-grade B-cell non-Hodgkin's lymphoma associated with cold agglutinin syndrome, cytogenetically characterized by partial trisomy 3, are presented in this report. Our data suggest that the long arm of chromosome 3 might be of particular importance in the pathogenesis of this subgroup of lymphomas.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Anemia, Hemolytic, Autoimmune / complications*
Anemia, Hemolytic, Autoimmune / genetics*
Chromosomes, Human, Pair 3 / genetics*
Female
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Lymphoma, B-Cell / complications*
Lymphoma, B-Cell / genetics*
Lymphoma, Non-Hodgkin / complications*
Lymphoma, Non-Hodgkin / genetics*
Male
Trisomy / genetics*