Breath-hold T2-weighted MRI of hepatic tumors: value of echo planar imaging with diffusion-sensitizing gradient

J Comput Assist Tomogr. 1998 May-Jun;22(3):364-71. doi: 10.1097/00004728-199805000-00005.

Abstract

Purpose: The purpose of our study was to evaluate the efficacy of echo planar imaging (EPI) as a breath-holding T2-weighted technique for imaging focal hepatic lesions.

Method: Forty-eight patients with focal hepatic lesions (9 metastases, 21 hepatocellular carcinomas, 1 cholangiocarcinoma, 16 hemangiomas, and 2 cysts) underwent single shot EPI with and without a small diffusion-sensitizing gradient (DSG) (beta values = 55 s/mm2) at 1.5 T. Comparison was made with breath-holding T2-weighted fast SE (FSE) sequences.

Results: Lesion-to-liver signal intensity ratio of EPI was significantly better than that of T2-weighted FSE (p < 0.05) in patients with metastasis. Use of DSG suppressed bright signals from vessels or periportal tissue, resulting in better conspicuity of small lesions. EPI with DSG visualized more metastatic deposits than T2-weighted FSE (p < 0.01).

Conclusion: EPI with a small DSG is helpful for detection of small hepatic metastases.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Hepatocellular / diagnosis
  • Cholangiocarcinoma / diagnosis
  • Cysts / diagnosis
  • Diffusion
  • Echo-Planar Imaging / methods*
  • Evaluation Studies as Topic
  • Female
  • Hemangioma / diagnosis
  • Humans
  • Image Enhancement / methods*
  • Kidney / pathology
  • Liver / blood supply
  • Liver / pathology
  • Liver Diseases / diagnosis
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / secondary
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Portal Vein / pathology
  • Respiration
  • Spleen / pathology