Renal artery stenosis and accessory renal arteries: accuracy of detection and visualization with gadolinium-enhanced breath-hold MR angiography

Radiology. 1998 May;207(2):497-504. doi: 10.1148/radiology.207.2.9577501.

Abstract

Purpose: To determine the accuracy of gadolinium-enhanced breath-hold magnetic resonance (MR) angiography in the diagnosis of renal artery stenosis and visualization of accessory renal arteries.

Materials and methods: Forty-four patients suspected of having renal artery stenosis and 10 potential kidney donors, all of whom were scheduled to undergo elective intraarterial digital subtraction angiography (DSA), were studied. Three-dimensional gradient-echo gadolinium-enhanced MR angiography was performed at 1.5 T with the following parameters: repetition time, 13.5 msec; echo time, 3.5 msec; flip angle, 60 degrees; 195 x 512 matrix; 400-mm field of view; and 6-cm imaging volume consisting of 15 4-mm-thick partitions reconstructed every 2 mm. Gadopentetate dimeglumine (30 mL) was injected with a power injector. MR angiograms were assessed before the standard of reference, intraarterial DSA, was performed.

Results: Four MR angiograms were not evaluable because of poor image quality. MR angiography enabled visualization of all but one of the 121 arteries. In four small accessory arteries, a stenosis could not be excluded owing to inadequate spatial resolution. MR angiography enabled the correct diagnosis in 30 of the 31 arteries with a grade 2 (50%-99%) stenosis and in seven of the 10 occluded arteries. Sensitivity and specificity for correct identification of a grade 2 stenosis were 97% and 92%, respectively.

Conclusion: Gadolinium-enhanced MR angiography is an accurate, minimally invasive method for detecting renal artery stenosis and is reliable for visualizing accessory renal arteries.

MeSH terms

  • Adult
  • Aged
  • Angiography, Digital Subtraction
  • Collateral Circulation*
  • Contrast Media* / administration & dosage
  • Creatinine / blood
  • Female
  • Gadolinium DTPA* / administration & dosage
  • Humans
  • Hypertension / complications
  • Image Enhancement
  • Image Processing, Computer-Assisted
  • Injections, Intra-Arterial
  • Injections, Intravenous
  • Kidney Transplantation
  • Magnetic Resonance Angiography*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Renal Artery / diagnostic imaging
  • Renal Artery / pathology*
  • Renal Artery Obstruction / diagnosis*
  • Renal Artery Obstruction / diagnostic imaging
  • Reproducibility of Results
  • Respiration
  • Sensitivity and Specificity
  • Tissue Donors

Substances

  • Contrast Media
  • Creatinine
  • Gadolinium DTPA