Dual determination of angiotensin-converting enzyme and angiotensin-II type 1 receptor genotypes as predictors of restenosis after coronary angioplasty

M Hamon; C Amant; C Bauters; F Richard; N Helbecque; F Passard; E P McFadden; J M Lablanche; M E Bertrand; P Amouyel

doi:10.1016/s0002-9149(97)00852-7

Dual determination of angiotensin-converting enzyme and angiotensin-II type 1 receptor genotypes as predictors of restenosis after coronary angioplasty

Am J Cardiol. 1998 Jan 1;81(1):79-81. doi: 10.1016/s0002-9149(97)00852-7.

Authors

M Hamon¹, C Amant, C Bauters, F Richard, N Helbecque, F Passard, E P McFadden, J M Lablanche, M E Bertrand, P Amouyel

Affiliation

¹ University and Center Hospitalier Régional Universitaire, Lille, France.

PMID: 9462611
DOI: 10.1016/s0002-9149(97)00852-7

Abstract

This study sought to assess the potential influence of the angiotensin-converting enzyme (ACE) and angiotensin II type 1 (AT1) receptor gene polymorphisms on restenosis after coronary balloon angioplasty. The authors conclude that screening for genetic suspectibility to restenosis based on genotyping of ACE and AT1 receptor polymorphisms before conventional balloon angioplasty is not clinically useful.

MeSH terms

Angioplasty, Balloon, Coronary*
Coronary Disease / genetics*
Coronary Disease / metabolism
Coronary Disease / therapy*
Female
Follow-Up Studies
Gene Deletion
Gene Frequency
Genetic Testing
Genotype
Humans
Male
Middle Aged
Peptidyl-Dipeptidase A / blood*
Polymorphism, Genetic / genetics*
Receptor, Angiotensin, Type 1
Receptors, Angiotensin / blood*
Recurrence

Substances

Receptor, Angiotensin, Type 1
Receptors, Angiotensin
Peptidyl-Dipeptidase A